Results 111 to 120 of about 1,595,190 (307)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Law, Property, and Marital Dissolution [PDF]
This paper challenges the view that legal rights are not important in affecting whether people divorce, but it puts as much emphasis on property rights (given, for example, by the law on alimony) as on dissolution rights.
Simon Clark
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Is there a place for work in child development? Implications of child development theory and research for interpretation of the UN Convention on the Rights of the Child, with particular reference to Article 32, on children, work and exploitation [PDF]
, 1999 This paper is about the role of child-development knowledge and research in international efforts to improve the lives and prospects for millions of working children.
Woodhead, Martin
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The Non-government Report on the Implementation of the Convention on the Rights of the Child in Australia, Contribution by SCALES authors [PDF]
, 2005 This non-government report to the United Nations Committee on the Rights of the Child responds to the Australian Government’s Combined Second and Third Reports and makes recommendations to further Australia’s compliance with the United Nations Convention
National Children’s and Youth Law Centre and Defence for Childre,
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Revista Facultad de Jurisprudencia, 2019 Adoption rates in Chile, in relation to the number of children placed in alternative care systems, are considerably low. Although there are a multiplicity of factors that motivate the previous situation, one that we consider of particular relevance, is ...
Alejandra Illanes Valdés
doaj
Rethinking Visitation: From a Parental to a Relational Right [PDF]
, 2009 [...] visitation rights are considered to arise from the very fact of parenthood, so that parents are entitled to this right simply by being legally recognized as parents.
Blecher-Prigat, Ayelet
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source