Results 31 to 40 of about 956,438 (274)

Sensing and Modulation of Invadopodia across a Wide Range of Rigidities [PDF]

Biophysical Journal, 2011
Recent studies have suggested that extracellular matrix rigidity regulates cancer invasiveness, including the formation of cellular invadopodial protrusions; however, the relevant mechanical range is unclear. Here, we used a combined analysis of tissue-derived model basement membrane (BM) and stromal matrices and synthetic materials to understand how ...
Parekh, Aron, Ruppender, Nazanin S., Branch, Kevin M., Sewell-Loftin, M.K., Lin, Jun, Boyer, Patrick D., Candiello, Joseph E., Merryman, W. David, Guelcher, Scott A., Weaver, Alissa M.   +9 more
openaire   +2 more sources

Acto-myosin based response to stiffness and rigidity sensing [PDF]

Cell Adhesion & Migration, 2011
Cells sense the rigidity of their environment and respond to it. Most studies have been focused on the role of adhesion complexes in rigidity sensing. In particular, it has been clearly shown that proteins of the adhesion complexes were stretch-sensitive, and could thus trigger mechano-chemical signaling in response to applied forces.
Jonathan, Fouchard, Démosthène, Mitrossilis, Atef, Asnacios   +2 more
openaire   +2 more sources

Probing mechanobiological role of filamin A in migration and invasion of human U87 glioblastoma cells using submicron soft pillars

Nano Convergence, 2021
Filamin A (FLNa) belongs to an actin-binding protein family in binding and cross-linking actin filaments into a three-dimensional structure. However, little attention has been given to its mechanobiological role in cancer cells.
Abdurazak Aman Ketebo, Chanyong Park, Jaewon Kim, Myeongjun Jun, Sungsu Park   +4 more
doaj   +1 more source

Dynamic mechanisms of cell rigidity sensing: insights from a computational model of actomyosin networks. [PDF]

PLoS ONE, 2012
Cells modulate themselves in response to the surrounding environment like substrate elasticity, exhibiting structural reorganization driven by the contractility of cytoskeleton. The cytoskeleton is the scaffolding structure of eukaryotic cells, playing a
Carlos Borau, Taeyoon Kim, Tamara Bidone, José Manuel García-Aznar, Roger D Kamm   +4 more
doaj   +1 more source

Equalization of force resolutions for forceps force sensors with double diaphragm spring structure

Nihon Kikai Gakkai ronbunshu, 2017
In minimally invasive surgery robots, force sensing is required to improve its manipulability. To perform delicate surgery, three-axis force sensing is desired.
Satsuya NODA, Toshio TAKAYAMA, Toru OMATA   +2 more
doaj   +1 more source

Dual-Responsive Photonic Crystal Sensors Based on Physical Crossing-Linking SF-PNIPAM Dual-Crosslinked Hydrogel

Gels, 2022
Flexible wearable materials have frequently been used in drug delivery, healthcare monitoring, and wearable sensors for decades. As a novel type of artificially designed functional material, photonic crystals (PCs) are sensitive to the changes in the ...
Wenxiang Zheng, Xiaolu Cai, Dan Yan, Ghulam Murtaza, Zihui Meng, Lili Qiu   +5 more
doaj   +1 more source

Exploiting Firm Capabilities by Sensing, Seizing and Reconfiguring Capabilities: An Empirical Investigation

Economic and Business Review, 2019
The aim of this paper is to study the exploitation of firm capabilities as dynamic capabilities through sensing, seizing and reconfiguring capabilities.
Lidija Breznik, Matej Lahovnik, Vlado Dimovski   +2 more
doaj   +1 more source

A Multifunctional Bioelectronic Device with Switchable Rigidity and Reconfigurable Shapes for Comprehensive Diagnosis

Advanced Electronic Materials, 2023
Soft bioelectronic devices have potential in medical applications, especially comprehensive diagnoses that rely on immovable equipment to acquire multiple physiological signals.
Yang Jiao, Yingchao Zhang, Haijun Feng, Haibo Li, Zhouheng Wang, Peng Wang, Yutong Wang, Ning Zheng, Tao Xie, Yinji Ma, Xue Feng   +10 more
doaj   +1 more source

Development of a High-Throughput Low-Cost Approach for Fabricating Fully Drawn Paper-Based Analytical Devices Using Commercial Writing Tools

Chemosensors, 2021
This work reports the development and optimization of a rapid and low-cost pen-on-paper plotting approach for the fabrication of paper-based analytical devices (PADs) using commercial writing stationery.
Varvara Pagkali, Eleftheria Stavra, Dionysios Soulis, Anastasios Economou   +3 more
doaj   +1 more source

From stress fiber to focal adhesion: a role of actin crosslinkers in force transmission

Frontiers in Cell and Developmental Biology
The contractile apparatus, stress fiber (SF), is connected to the cell adhesion machinery, focal adhesion (FA), at the termini of SF. The SF-FA complex is essential for various mechanical activities of cells, including cell adhesion to the extracellular ...
Hiroki Katsuta, Masahiro Sokabe, Hiroaki Hirata   +2 more
doaj   +1 more source