Results 201 to 210 of about 65,860 (259)

The Interference of RNA Preservative and Post-Collection Interval on RNA Integrity from Different Mice Tissues. [PDF]

Genes (Basel)
Xie T, Zhu H, Wang X, Li F, Wang A, Zhang Y, Zhang S, Guo D.   +7 more
europepmc   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Altered amplitudes of low-frequency fluctuations in primary open angle glaucoma patients: a resting-state fMRI study. [PDF]

Int J Ophthalmol
Huang Y, Luo HD, Shu YQ, Ouyang F, Song YN, Wang YY, Yu XQ, Xiong C, Yang L, Zhang X.   +9 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Bio-RegNet: A Meta-Homeostatic Bayesian Neural Network Framework Integrating Treg-Inspired Immunoregulation and Autophagic Optimization for Adaptive Community Detection and Stable Intelligence. [PDF]

Biomimetics (Basel)
Ma Y, Qu D, Pyrozhenko M.
europepmc   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Analytical Validation of NETest2.0^®, a Novel Multigene Blood-Based Molecular Assay for Neuroendocrine Tumors. [PDF]

Cancers (Basel)
Kidd M, Koduru SV, Halim A.
europepmc   +1 more source

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

The FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong, Elisa Lazzari, Sabrina Pacor, Simeone Dal Monego, Erica Piovesan, Danilo Licastro, Germana Meroni   +6 more
wiley   +1 more source

Association Between Regular Dental Scaling and Risk of Dementia in Patients With Moderate to Severe Periodontitis Longitudinal Study Using Korean National Health Insurance Service‐National Health Screening Cohort Data Base

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives This study aimed to determine the effectiveness of regular dental scaling by evaluating the association between the frequency of dental scaling and the risk of dementia in individuals with moderate to severe periodontal disease. Methods This study used the Korean National Health Insurance Service‐National Health Screening cohort ...
Seon‐Rye Kim, Minkook Son, Yu‐Rin Kim   +2 more
wiley   +1 more source

Tandem MADS-Box Genes FUL2 and MADS1 Form a Regulatory Module to Repress Serotonin Biosynthesis via Direct ASMT5 Activation in Tomato Fruit. [PDF]

Plant Biotechnol J
Xu Y, Jia H, Tang D, Zhang L, Liu X, Rong J, Lv Y, Lang Z, Niu Q.   +8 more
europepmc   +1 more source