Bidirectional Synthesis of the IJK Fragment of Ciguatoxin CTX3C by Sequential Double Ring-Closing Metathesis and Tsuji-Trost Allylation. [PDF]
Org Lett, 2020 Popadynec M, Gibbard H, Clark JS.
europepmc +1 more source
Reversible Dihydrogen Splitting and Diradical Reactivity of 1,4‐Digermabenzene‐1,4‐diide
ChemistryEurope, Volume 4, Issue 5, May 2026.The diradical reactivity of the 1,4‐digermabenzene‐1,4‐diide, [(ADC)Ge]2, has been demonstrated with a range of substrates. Notably, it undergoes reversible dihydrogen splitting and radical coupling with TEMPO (2,2,6,6‐tetramethylpiperidinyloxyl = RO), forming [(ADC)GeH]2 and [(ADC)Ge(OR)]2, respectively.
Falk Ebeler +5 more
wiley +1 more source
Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis
ChemistryEurope, Volume 4, Issue 5, May 2026.Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
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Scratch‐Healing of Conjugated Polymers: Flexibly Linked PTB7‐Th Copolymers and Their Blends
Macromolecular Chemistry and Physics, Volume 227, Issue 9, 15 May 2026.Flexibly‐linked conjugated polymers based on the donor polymer PTB7‐Th are capable of scratch healing. A higher linker content leads to higher “mobility,” which is required for the healing process. However, the optical properties are impaired. Blends of donor polymers with high and low linker content can solve this dilemma as they provide sufficient ...
Marc Sommer +8 more
wiley +1 more source
Journal of Polymer Science, Volume 64, Issue 9, Page 1860-1894, 1 May 2026.This review examines bio‐based polyurethanes from renewable feedstocks, focusing on structure‐property relationships governing mechanical performance. It analyzes reinforcement strategies, benchmarks against petrochemical counterparts, and explores future directions, including non‐isocyanate routes and circular economy integration for sustainable high ...
Khaled Chawraba +4 more
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Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation
Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.The total synthesis of the bis‐indole alkaloid (−)‐owerreine has been accomplished by a diastereoselective [4+2] annulation between an enamine and an α,β−unsaturated indolenine precursor to form the 3‐spirocyclic tetrahydropyridine linkage of the natural product. DFT calculations allow an understanding of the mechanism of the key annulation.
Elisa Coll +4 more
wiley +2 more sources
"Close-to-Release": Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis. [PDF]
J Am Chem Soc, 2019 Sabatino V, Rebelein JG, Ward TR.
europepmc +1 more source
Programmable Artificial-Cellular Membrane Dynamics via Ring-Closing Metathesis. [PDF]
J Am Chem SocHamaguchi R +3 more
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Efficient convergent synthesis of 1,3-diazepinone nucleosides by ring-closing metathesis and direct glycosylation. [PDF]
RSC AdvHedger AK +5 more
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Optimized Ring Closing Metathesis Reaction Conditions To Suppress Desallyl Side Products in the Solid-Phase Synthesis of Cyclic Peptides Involving Tyrosine(O-allyl). [PDF]
J Org Chem, 2020 Gisemba SA, Aldrich JV.
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