Results 91 to 100 of about 284,604 (310)

Novel Reversible Fluorescent Glycan Linker for Functional Glycomics

, 2019
To aid in generating complex and diverse natural glycan libraries for functional glycomics, more efficient and reliable methods are needed to derivatize glycans.
Nan Jia (118883), Tanya R. McKitrick (7543058), Lijun Sun (219532), Mohui Wei (1574764), Chao Gao (154531), Akul Y. Mehta (1315050), Alyssa M. McQuillan (7543061), Richard D. Cummings (52654), Jamie Heimburg-Molinaro (276894)   +8 more
core   +1 more source

Síntesis y caracterización de complejos organometálicos de Ru(II) y Co(II) a partir de ligandos bisimidazolio como organocatalizadores en el acoplamiento de CO2 y epóxidos para la obtención de carbonatos cíclicos

, 2022
En este trabajo se realizó la síntesis de dos ligandos nuevos: dibromuro de 3,3'-metilenobis(1-(6-(terbutoxi)piridin-2-ilo)-1H-imidazol-3-io) (L1) y dibromuro de 3,3'-metilenobis(1-(6-hidroxipiridin-2-ilo)-1H-imidazol-3-io) (L2).
Ezenarro Salcedo, David Enrique
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Celebrating Soft Matter's 10th Anniversary: Topology matters: structure and dynamics of ring polymers

, 2015
Considering topology among all polymer architectures polymer rings are unique, as they are the simplest closed structures without ends. In this review we present recent experimental advances addressing the structure and dynamics of rings. We focus mainly
Wischnewski, A., Richter, D., Goossen, Sebastian   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Christmas Symposium Basel December 6, 2019

CHIMIA, 2020
Daniel Joss, Ivan Urosev, Ksenia Reznikova, Nadja Niggli, Gosia Murawska, Dzmitry Miarzlou, Claire Meyer, Patrick Herr, Fadri Christoffel, Vittoria Chimisso, Alain Baiyoumy, Jaicy Vallapurackal, Puck van Gerwen   +12 more
doaj   +1 more source

An investigation of the observed, but counter-intuitive, stereoselectivity noted during chiral amine synthesis via N-chiral-ketimines

Beilstein Journal of Organic Chemistry, 2013
The default explanation for good to high diastereomeric excess when reducing N-chiral imines possessing only mediocre cis/trans-imine ratios (>15% cis-imine) has invariably been in situ cis-to-trans isomerization before reduction; but until now no study ...
Thomas C. Nugent, Richard Vaughan Williams, Andrei Dragan, Alejandro Alvarado Méndez, Andrei V. Iosub   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Analysis of Tree–ring Chemistry to Interpret Variations in Tree–ring Growth of Larix leptolepis and Cryptomeria japonica in Relation to Atmospheric Environmental Changes in Southern Korea

, 2015
Annual tree rings may have information to help investigate the effects of environmental change caused by temperature, air pollution, and acid rain on tree growth.
Ohga, Shoji, Lee, Kye-Han, Choi, Woo-Jung, Luong, Thi-Hoan, Park, Gwan-Soo, Oga, Shoji, Jang, Kyoung-Soo, 大賀, 祥治   +7 more
core