Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Cyclopentadienyl Ligands in Lanthanide Single-Molecule Magnets: One Ring To Rule Them All?
Accounts of Chemical Research, 2018 The discovery of materials capable of storing magnetic information at the level of single molecules and even single atoms has fueled renewed interest in the slow magnetic relaxation properties of single-molecule magnets (SMMs).
Benjamin M. Day +2 more
semanticscholar +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Studies on the Chemistry of the Living Bark of the Black Locust Tree in Relation to Frost Hardiness. IV. Effects of Ringing on Translocation, Protein Synthesis and the Development of Hardiness [PDF]
, 1953 D. Siminovitch, David Briggs
openalex +1 more source
The chemistry of enaminones, diazocarbonyls and small rings: our contribution [PDF]
Journal of the Brazilian Chemical Society, 2003 After thirty two years in Brazil and retired from Universidade Estadual de Campinas the author wishes to present this account, a summary of a large part of the research in synthetic methodology developed by the research groups of Albert J. Kascheres and the author at Universidade Estadual de Campinas Chemistry Institute. Contributions have been made to
openaire +6 more sources
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Types and properties of metal-free catalysts for living polymerizations of biomaterials [PDF]
, 2008 Syntéza biokompatibilních a biodegradabilních polyesterů, použitelných převážně v medicíně, využívá pro polymeraci za otevření kruhu katalyzátory na bázi kovu (např. Sn, Al atd.), které se mohou po implantaci deponovat v těle.
Repka, Martin
core
Spatially Resolved Chemistry in Nearby Galaxies II. The Nuclear Bar in Maffei 2
, 2012 We present 2" - 10" imaging of eleven transitions from nine molecular species across the nuclear bar in Maffei 2. The data were obtained with the BIMA and OVRO interferometers. The ten detected transitions are compared with existing CO isotopologues, HCN,
Meier, David S., Turner, Jean L.
core +1 more source
CHEMISTRY OF SUBSTITUTED RING COMPOUNDS. PART I. SYNTHESIS OF ααγ TRIMETHYLCYCLOPENTANONE. [PDF]
, 1939 MUHAMINIAD QUDRAT-I-KHUDA +1 more
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source