Results 151 to 160 of about 2,813,819 (368)

Novel "green" catalysts for controlled ring-opening polymerization of lactide [PDF]

, 2010
Syntéza polylaktidu (PLA) polymerací za otevření kruhu cyklického monomeru (ROP) může být uskutečněna různými způsoby. Literatura uvádí více než 100 katalytických systémů, jejichž pomocí lze polylaktid a jiné biodegradabilní alifatické polyestery získat.
Surman, František
core  

Ringing medicinal chemistry: The importance of 3-membered rings in drug discovery

Bioorganic & Medicinal Chemistry
Scaffold-based drug design has become increasingly prominent in the pharmaceutical field due to the systematic and effective approach through which it facilitates the development of novel drugs. The identification of key scaffolds provides medicinal chemists with a fundamental framework for subsequent research.
Sahani Sandalima, Uthumange, Angie Jun Hui, Liew, Xavier Wezen, Chee, Keng Yoon, Yeong   +3 more
openaire   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Combination of ring-opening polymerization and “click” chemistry towards functionalization of aliphatic polyesters [PDF]

, 2005
Raphaël Riva, Stéphanie Schmeits, François Stoffelbach, Christine Jérôme, Robert Jérôme, Philippe Lecomte   +5 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Basel Chemistry Symposium 2014 In Memory of Prof. T. Reichstein

CHIMIA, 2015
Christophe Daeppen, Markus Gantenbein, Michel Rickhaus, Lukas Jundt, Martin Rother, Charlotte Laupheimer, Isabel Kerschgens, Andrea Pannwitz, Daniel Bachmann, Ina Bodoky   +9 more
doaj   +1 more source

Studies in Chlorin Chemistry. 3. A Practical Synthesis of C,D-Ring Symmetric Chlorins of Potential Utility in Photodynamic Therapy [PDF]

, 2006
William G. O’Neal, William P. Roberts, Indranath Ghosh, Hui Wang, Peter A. Jacobi   +4 more
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Basel Chemistry Christmas Symposium 2015

CHIMIA, 2016
Andrea Pannwitz, Serena Rigo, Linda Bannwart, Lorenzo Bizzini, Sabine Malzkuhn, Thomas Müntener, Charlotte Laupheimer   +6 more
doaj   +1 more source

Chemistry of quinuclidines as nitrogen bicyclic bridged‐ring structures [PDF]

, 2006
Wafaa S. Hamama, Osama M. Abd El‐Magid, Hanafi H. Zoorob   +2 more
openalex   +1 more source