Results 151 to 160 of about 856,718 (308)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

PCC Christmas Symposium Basel 2024

CHIMIA
Pieter Brongers, Tzu-Chin Chang Chien, Elinor Morris, Ilse Friedländer, Richard Karl, Salome L. Heim, Elizaveta Maksimova, Livia Müller, Andreas Ostertag, Carlotta Seno, Benjamin Vermeer, Chiara Disraeli, Minqi Pan, Anies Rösch, Stephan Schumann, Luise Sokoliuk, Dorothee Wagner, Joël Wellauer, Amine Yücekul   +18 more
doaj   +1 more source

Chemistry of Fairy Ring and Possibility of “Fairy Chemicals” as a Plant Growth Regulator

, 2014
Hirokazu Kawagishi
openalex   +2 more sources

Beiträge zur Chemie des Phosphors, 80 [1] Über die Phosphor-Bor-Dreiringverbindung (t-BuP)₂BN(i-Pr)₂ / Contributions to the Chemistry of Phosphorus, 80 [1] About the Phosphorus Boron Three-Membered Ring Compound (t-BuP)₂BN(i-Pr)₂ [PDF]

, 1978
Marianne Bäudler, A. Marx, Josef Hahn
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

PCC Christmas Symposium Basel 2023

CHIMIA
Gladwin Suryatin Alim, Tzu-Chin Chang Chien, John Coats, Ilse Friedländer, Salome Heim, Bradley Higginson, Annika Huber, Charlotte Kress, Anton Kudashev, Elizaveta Maksimova, Elinor Morris, Livia Müller, Andreas Ostertag, Mahsa Parvizian, Carlotta Seno, Dorothee Wagner, Joël Wellauer   +16 more
doaj   +1 more source

Recent Progress in the Chemistry of Ring‐Fused Azulenes: Synthesis, Reactivity and Properties [PDF]

Taku Shoji, Shunji Ito
openalex   +1 more source

Gas-phase chemistry of acylium ions. Seven-to-five ring contraction of 1,3-dioxepane and 1,3-dioxep-5-ene [PDF]

, 1999
Luiz Alberto Beraldo de Moraes, Tapio Kotiaho, Marcos N. Eberlin   +2 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source