Results 211 to 220 of about 853,691 (310)

Regulating Protein Immobilization During Cell‐Free Protein Synthesis in Hyaluronan Microgels

Advanced Biology, EarlyView.
Bifunctional microgels carrying a linear DNA template and Ni2+‐activated NTA moieties are used as platform for cell‐free protein synthesis and in situ protein immobilization. By varying the concentration of NTA moieties in the microgels, the amount of GFP‐His immobilized inside the microgel and released to the microgel environment can be regulated ...
Anika Kaufmann, Kateryna Ivanova, Julian Thiele   +2 more
wiley   +1 more source

Enantio-, atrop-, and diastereoselective macrolactonization to access type III cyclophanes. [PDF]

Nat Commun
Wang J, Lv K, Wen Y, Liu T, Zhao C.
europepmc   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

Advanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker, Ido Galil, Omer Kfir, Gal Chen, Rotem Menachem, Jeny Shklover, Avi Schroeder, Shanny Ackerman   +7 more
wiley   +1 more source

Stereospecific access to α-haloalkyl esters <i>via</i> enol ester epoxides and synthesis of a C3-C21 fragment of bastimolide A.

Org Biomol Chem
Howell LW, Hackbarth JN, Abraham JS, Friestad GK.   +3 more
europepmc   +1 more source

Structure-property relationships for the force-triggered disrotatory ring-opening of cyclobutene. [PDF]

Chem Sci
Bowser BH, Brown CL, Meisner J, Kouznetsova TB, Martinez TJ, Craig SL.   +5 more
europepmc   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

Palladium-Catalyzed Site-Selective Regiodivergent Carbocyclization of Di- and Trienallenes: A Switch between Substituted Cyclohexene and Cyclobutene. [PDF]

J Am Chem Soc
Kong WJ, Wu H, Chen JY, Liao RZ, Liu Y, Luo Z, Pires Vilela I, Fang P, Himo F, Bäckvall JE.   +9 more
europepmc   +1 more source

Relationship between interaction geometry and cooperativity measured in H-bonded networks of hydroxyl groups. [PDF]

Chem Sci
Trevisan L, Bond AD, Hunter CA.
europepmc   +1 more source

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

Advanced Engineering Materials, EarlyView.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng, Ziping Sang, Jiali Zhang, Felix Radtke, Louis Becker, Simone Herzog, Sebastian Weber, Christoph Broeckmann   +7 more
wiley   +1 more source

Pyrrolidine synthesis via ring contraction of pyridines. [PDF]

Nat Commun
Ueno R, Hirano S, Takaya J.
europepmc   +1 more source