Results 211 to 220 of about 2,813,819 (368)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Photochemical Reactions of Aromatic Compounds. XLVI. Stereochemical Reaction Courses in the Photolytic Ring-Cleavage Reactions of Diarylcyclobutanes: Implications of Conformation-Controlled Orbital Interactions in the Excited-State Chemistry [PDF]

, 1989
Chyongjin Pac, Kazuyoshi Go-an, Shozo Yanagida   +2 more
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Diastereoselective synthesis of multi-substituted cyclobutanes via catalyst-controlled regiodivergent hydrophosphination of acyl bicyclobutanes. [PDF]

Nat Commun
He HX, Wu F, Wang KJ, Wang L, Feng JJ.
europepmc   +1 more source

Interdisciplinary study of Gulf Stream warm core ring physics, chemistry, and biology : report of the Warm Core Rings Data Workshop, July 6-19, 1983, Whispering Pines Conference Center, W. Alton Jones Campus, University of Rhode Island, West Greenwich, Rhode Island [PDF]

, 1983
Peter H. Wiebe
openalex   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Stereospecific Insertion of Cyclic Amidines into Aryl-Substituted Cyclopropanones: Access to Complex Spirocyclic Aminals. [PDF]

Org Lett
Herzog R, Agrawal I, von Köller HF, Kloiber K, Werz DB.   +4 more
europepmc   +1 more source

Warm core rings : an interdisciplinary study of warm core ring physics, chemistry, and biology; R/V Endeavor, R/V Atlantis II September/October 1981 cruise reports [PDF]

, 1981
Terrence M. Joyce, Peter H. Wiebe
openalex   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Dihapto-Coordinated Conjugated Carbocycles (η²-C_<i>n</i>H_<i>n</i> <i>n</i> = 5-8): Blurring the Line Between Aromatic and Antiaromatic Hydrocarbons. [PDF]

J Am Chem Soc
Ericson MN, Heman-Ackah JK, Lombardo RF, Meng AQ, Ortiz MR, Megert SE, Dickie DA, Harman WD.   +7 more
europepmc   +1 more source