Results 71 to 80 of about 243,777 (279)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

High-Secure Fingerprint Authentication System Using Ring-LWE Cryptography

IEEE Access, 2019
This paper presents a high-secure fingerprint authentication system using ring learning with errors (ring-LWE) cryptography to protect users' fingerprint data more securely.
Tuy Nguyen Tan, Hanho Lee
doaj   +1 more source

Design and Implementation of Constant-Round Dynamic Group Key Exchange from RLWE

IEEE Access, 2020
Group Key Exchange (GKE) is required for secure group communication with high confidentiality. In particular, a trusted authority can handle issues that happen by the malicious actions of group members, but it is expensive to deploy and not suitable in a
Rakyong Choi, Dongyeon Hong, Seongho Han, Seunggeun Baek, Wooseok Kang, Kwangjo Kim   +5 more
doaj   +1 more source

PyHST2: an hybrid distributed code for high speed tomographic reconstruction with iterative reconstruction and a priori knowledge capabilities

, 2013
We present the PyHST2 code which is in service at ESRF for phase-contrast and absorption tomography. This code has been engineered to sustain the high data flow typical of the third generation synchrotron facilities (10 terabytes per experiment) by ...
Brun, Emmanuel, Gouillart, Emmanuelle, Kieffer, Jerome, Mirone, Alessandro, Tafforeau, Paul   +4 more
core   +2 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Dynamic Multi-Key Block Binary Ring-Compact Bootstrapping

Mathematics
Multi-Key Fully Homomorphic Encryption (MK-FHE) is essential for secure multi-party computation but currently faces significant scalability bottlenecks due to linear computational growth and low bootstrapping throughput.
Qiwei Xiao, Ruwei Huang
doaj   +1 more source

One-Shot Learning of Manipulation Skills with Online Dynamics Adaptation and Neural Network Priors

, 2016
One of the key challenges in applying reinforcement learning to complex robotic control tasks is the need to gather large amounts of experience in order to find an effective policy for the task at hand. Model-based reinforcement learning can achieve good
Abbeel, Pieter, Fu, Justin, Levine, Sergey   +2 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparing instance-averaging with instance-saving learning algorithms [PDF]

, 1988
The goal of our research is to understand the power and appropriateness of instance-based representations and their associated acquisition methods. This paper concerns two methods for reducing storage requirements for instance-based learning algorithms ...
Aha, David W., Kibler, Dennis
core