Results 161 to 170 of about 25,768 (299)

Interpretable Machine Learning Framework for Nb─Si Based Alloy Design with Enhanced Fracture Toughness

open access: yesAdvanced Science, EarlyView.
An interpretable machine learning framework integrating SHAP and PDP analysis identifies critical design descriptors from 139 physicochemical features for Nb─Si alloys. The framework achieves <7% prediction error and guides the discovery of Nb38.5Ti38.5Si3Zr18V2 alloy with 22.791 MPa·m1/2 fracture toughness, breaking the 20 MPa·m1/2 barrier.
Dezhi Chen   +7 more
wiley   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

open access: yesAdvanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang   +19 more
wiley   +1 more source

Unconventional Hysteretic Charge Filling in Moiré‐Reconstructed Helical Trilayer Graphene

open access: yesAdvanced Science, EarlyView.
In helical trilayer graphene, sequential twisting reconstructs the moiré landscape into periodic domains separated by aperiodic boundaries. Longitudinal transport reveals sweep‐direction‐dependent hysteresis, while the Hall response traces this behavior to hysteretic charge filling at the aperiodic boundaries.
Hangyeol Park   +9 more
wiley   +1 more source

The serine-arginine-rich protein PfSR-X2 modulates human malaria parasite gene expression during the intraerythrocytic developmental cycle. [PDF]

open access: yesFront Cell Infect Microbiol
Hu Y   +12 more
europepmc   +1 more source

Wave dissipation patterns as an indicator of rip current hazard

open access: yes, 2017
Rip currents (rips) are hazardous offshore-directed flows in the surfzone of beaches worldwide. Rips are a major hazard for recreational beach use and are the dominant cause of beach rescues and drownings.
Pitman, Sebastian John
core  

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin   +15 more
wiley   +1 more source

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