Results 171 to 180 of about 76,315 (299)

Functional interactions among H2O2, NO, H2S, and melatonin in the physiology, metabolism, and quality of horticultural Solanaceae. [PDF]

J Exp Bot
Corpas FJ, Rivero RM, Freschi L, Palma JM.   +3 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Advances in Cell Wall Dynamics and Gene Expression in Postharvest Fruit Softening. [PDF]

Plants (Basel)
Wang X, Zhang D, Liu T, Yan Z, Ji X, Li Y, Wu Y, Cheng H, Wang Y, Cui J, Wu Y, Chen L.   +11 more
europepmc   +1 more source

Comparison Between the Soybean Seeds Ripened on a Highland and Those Ripened on a Lowland

, 1959
Ryozo Yamamoto, Masashi Ishikawa
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Regulatory role of calcium sulfide in ripening delay of postharvest bananas. [PDF]

Food Chem (Oxf)
Xu H, Bi X, Xing J, Guo M, Zhang H, Zhang X, Li W, Lei B.   +7 more
europepmc   +1 more source

Studies on Cheese Ripening

, 1959
Takeo Nakanishi
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Alternative splicing occurs in auxin-mediated trade-off between fruit development and quality in tomato. [PDF]

BMC Plant Biol
Ahiakpa JK, Munir S, Karikari B, Li F, Zhang X, Ge P, Tao J, Xu H, Ai G, Gai W, Zhang Y.   +10 more
europepmc   +1 more source

A Chromatographic Study of Cheddar Cheese Ripening

, 1956
D.H. Bullock, O.R. Irvine
openalex   +1 more source