Results 221 to 230 of about 118,983 (259)

Exogenous γ-aminobutyric acid application delays onset of ripening in Grenache, Chardonnay, and Shiraz grape berries. [PDF]

Plant Cell Physiol
Shekharappa CG, Booth NJ, Pagay V, Tyerman SD, Ramesh SA.   +4 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Ripening cycle and its relationship with fruiting in advanced <i>Coffea arabica</i> L. progenies derived from intra- and interspecific crosses. [PDF]

Front Plant Sci
Unigarro CA, Darghan AE, Cayón Salinas DG, Flórez-Ramos CP.   +3 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Roles of Eleven Key Enzymes in Sweet Value and Soluble Sugar Component Content During Mango Development. [PDF]

Int J Mol Sci
Li L, Wang Z, Li W, Li X, Zou K, Xie X, Liu C, Wu Y, Chen J, Huang G, Liu C.   +10 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Nitric oxide-centred signaling networks in plants: from growth to postharvest. [PDF]

Front Plant Sci
Sedlářová M, Jedelská T, Lebeda A, Petřivalský M.   +3 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Genome-Wide Identification and Functional Characterization of the Carboxylesterase (CXE) Gene Family in Melon (<i>Cucumis melo</i> L.): <i>CmCXE7</i> as a Cold-Responsive Regulator of Ester Metabolism. [PDF]

Plants (Basel)
Xia Y, Liu J, Zhang H, Huang Z, Zhu X, Li H.   +5 more
europepmc   +1 more source