Results 121 to 130 of about 2,978 (173)
The Necroptosis Adaptor RIPK3 Promotes Injury-Induced Cytokine Expression and Tissue Repair [PDF]
, 2014 SummaryProgrammed necrosis or necroptosis is an inflammatory form of cell death that critically requires the receptor-interacting protein kinase 3 (RIPK3).
McQuade, Thomas +5 more
core +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
MedComm, Volume 7, Issue 9, September 2026.This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Molecular MetabolismObjective: Aggregation of human islet amyloid polypeptide (hIAPP), a β-cell secretory product, leads to islet amyloid deposition, islet inflammation and β-cell loss in type 2 diabetes (T2D), but the mechanisms that underlie this process are incompletely ...
Noyonika Mukherjee +8 more
doaj +1 more source
Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease
MedComm, Volume 7, Issue 9, September 2026.Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi +6 more
wiley +1 more source
Role of RIPK3 in photodynamic therapy induced cell death
, 2011 La protéine RIPK3 (Receptor-interacting protein 3) a été montrée comme étant un activateur clé de la nécrose, mais il a également été constaté qu’il pouvait induire l’apoptose.
Fettweis, Grégory
core
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
MedComm – Oncology, Volume 5, Issue 3, September 2026.Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
Transforming Life Science Through Chromosome‐Level Genome Assemblies
Genes to Cells, Volume 31, Issue 5, September 2026.Chromosome‐level genome assemblies provide a framework for “glocal biology” in species of interest, linking local molecular features to chromosome architecture and evolutionary context. When integrated with pangenome analysis, comparative multi‐omics, genome language models, and experimental approaches, these assemblies enable hypothesis generation and
Tetsuo Kon +7 more
wiley +1 more source
Ripk1 and haematopoiesis: a case for LUBAC and Ripk3 [PDF]
Cell Death & Differentiation, 2018 Annibaldi, A, Meier, P
openaire +3 more sources
Journal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.ABSTRACT This current study aimed to decipher the anti‐inflammatory, anti‐ferroptosis and pronounced lung‐protective activities of Salvianolic acid B (Sal B) by integrating network pharmacology and experimental confirmation across multiple aspects. The optimal target protein and the relevant molecular mechanisms for Sal B in the context of ALI were ...
Hejun Gao +4 more
wiley +1 more source
, 2016 A20 is an anti-inflammatory protein linked to multiple human diseases, however the mechanisms by which A20 prevents inflammatory disease are incompletely defined.
Burlingame, Alma +16 more
core +1 more source