Results 91 to 100 of about 1,531,874 (315)
Effect of standardized training on the reliability of the Cochrane risk of bias assessment tool: a prospective study [PDF]
, 2017 BACKGROUND The Cochrane risk of bias tool is commonly criticized for having a low reliability. We aimed to investigate whether training of raters, with objective and standardized instructions on how to assess risk of bias, can improve the reliability ...
Peter Jüni +18 more
core +1 more source
The Newcastle–Ottawa Scale for Assessing the Quality of Studies in Systematic Reviews
PublicationsSecondary research is a cornerstone of health sciences, with substantial implications for clinical practice and health policy. Within the systematic review process, a key step is assessing study quality and risk of bias.
Emanuela Gualdi-Russo, Luciana Zaccagni
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Evidence-Based ToxicologyContext In vitro toxicity studies are increasingly being included as evidence in systematic reviews and chemical risk assessments. INVITES-IN, a tool for assessing the internal validity of in vitro studies, is under development in a process consisting of
Gro H. Mathisen +33 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Critical appraisal of systematic reviews and meta-analyses: a step-by-step guide for nephrologists
Renal FailureBackground Systematic reviews and meta-analyses play a pivotal role in evidence-based medicine, including nephrology, by consolidating findings from multiple studies. To maximize their utility, rigorous quality assessment during peer review is essential.
Wisit Cheungpasitporn +5 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Risk of bias according to revised Cochrane risk-of-bias tool for randomized trials.
, 2022 Risk of bias according to revised Cochrane risk-of-bias tool for randomized trials.
Pol Chewcharat (8436504) +6 more
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
, 2022 A: Risk of bias summary: review authors’ judgments about each risk of bias item for each included study. B: Risk of bias graph: review authors’ judgments about each risk of bias item presented as percentages across all included studies.
Nahla Ahmed El-Shahat (12334219) +6 more
core +1 more source