Results 51 to 60 of about 483,771 (216)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The Influence of Investor Sentiment on the South African Property Market: A Comparative Assessment of JSE Indices

International Journal of Financial Studies
Investor sentiment has increasingly been recognized as a behavioural factor influencing asset prices beyond traditional rational asset pricing models, yet evidence from South Africa’s property remains limited.
Charlize Nel, Fabian Moodley, Sune Ferreira-Schenk   +2 more
doaj   +1 more source

Establishing a link between risk tolerance, investor personality and behavioural finance in South Africa

Cogent Economics & Finance, 2018
The main objective of this paper was to establish which behavioural finance biases are associated with a certain level of risk tolerance and investor personality. Furthermore, the study aimed to indicate how these behavioural finance biases can influence
Zandri Dickason, Sune Ferreira
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Relationship Between Psychological Factors and Retirement Financial Plan and Its Gender Difference

Risks
As China’s population ages and the sustainability of the public pension system is at risk, personal savings become crucial. As such, the quality of financial planning for retirement (FPR) has been recognized as a key to safeguarding financial well-being ...
Han Ren, Thien Sang Lim
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Risk Perceptions of Insurance Policyholders in the Gauteng Region of South Africa

Acta Economica
The insurance industry’s product range is diverse, and the risk perception of each product differs from that of insurers, especially given the constantly changing market conditions.
Suné Ferreira-Schenk, Zandri Dickason-Koekemoer, Marko Van Deventer   +2 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Is Risk Tolerance the Missing Link? Unpacking the Drivers of Investment Intention and Gender Differences Among Generation Z

Jurnal Aplikasi Manajemen
The number of Single Investor Identification (SID) accounts is growing annually, primarily among Generation Z. However, a considerable disparity remains between those in this generation who have begun investing and those who have not.
Atmaya Fitra Alfathya, Sumiati, Nur Khusniyah Indrawati   +2 more
doaj   +1 more source

Determinants of Financial and Non-Financial Risk Tolerance among Students at Selected South African Universities

Foundations of Management, 2018
To enhance the portfolio allocation process, individuals need to understand their financial ability and psychological willingness to tolerate risks. To do this, their risk tolerance level must be quantified.
Ramudzuli Pfano Michael, Muzindutsi Paul-Francois   +1 more
doaj   +1 more source