Results 171 to 180 of about 449,299 (288)

Risky-choice framing effects persist when option descriptions are matched and complete: A replication and extension of DeKay and Dou (2024). [PDF]

Psychon Bull Rev
DeKay ML.
europepmc   +1 more source

Risk-taking unmasked: Using risky choice and temporal discounting to explain COVID-19 preventative behaviors. [PDF]

PLoS One, 2021
Byrne KA, Six SG, Anaraky RG, Harris MW, Winterlind EL.   +4 more
europepmc   +1 more source

Risky Business – The Role of Individual Risk Attitudes in Occupational Choice [PDF]

This study analyzes the relationship of individual risk attitudes and occupational sorting with respect to occupational earnings risk. By using the German Mikrozensus, a precise measure for earnings risk is computed as the occupation-wide standard ...
Ingo E. Isphording
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Deconstructing neural predictors of risky choice. [PDF]

PNAS Nexus
Mortazavi L, Wu CC, Ghasemi E, Knutson B.   +3 more
europepmc   +1 more source

Relying on the agent in charge of production for project evaluation [PDF]

I study the optimal project choice when the principal relies on the agent in charge of production for project evaluation. The principal has to choose between a safe project generating a fixed revenue and a risky project generating an uncertain revenue ...
Doh Shin Jeon
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Internal uncertainty impacts social information use in risky choice across adolescence. [PDF]

Commun Psychol
Ciranka S, van den Bos W.
europepmc   +1 more source

Household portfolios in the UK [PDF]

This paper presents a detailed analysis of the composition of household portfolios, using both aggregate and micro-data. Among the key findings are that: Most household wealth is held in the form of housing and pensions. Over time, there has been a shift
James Banks, Tanner, S
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source