Results 11 to 20 of about 29,100 (168)

Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film

Frontiers in Pharmacology, 2020
ObjectiveThe aim of the present study was to investigate the absorption routes as well as the potential application of the oral transmucosal delivery of risperidone orodispersible film (ODF) using physiologically based pharmacokinetic modeling.MethodsThe
Fang Chen, Hongrui Liu, Bing Wang, Liuliu Yang, Weimin Cai, Zheng Jiao, Zhou Yang, Yusheng Chen, Yingjun Quan, Xiaoqiang Xiang, Hao Wang   +10 more
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Effects of cannabidiol on vacuous chewing movements, plasma glucose and oxidative stress indices in rats administered high dose risperidone

Scientific Reports, 2022
Atypical antipsychotics, despite their rapid dissociation from dopamine receptors and reduced tendency to induce oxidative stress, have been associated with difficult-to-manage movement disorders, including tardive dyskinesia (TD).
Jaiyeola Abiola Kajero, Soraya Seedat, Jude Ohaeri, Abidemi Akindele, Oluwagbemiga Aina   +4 more
doaj   +1 more source

Can clinical parameters of patients, sans serum prolactin measurement, identify amenorrhea associated with risperidone use? Results from a cross-sectional analytical study

Journal of Current Research in Scientific Medicine, 2022
Background: Risperidone is a second-generation antipsychotic, which exerts its action by antagonizing dopamine (D2) and serotonin (5-HT2A) receptors. Amenorrhea is a common adverse effect observed in risperidone.
Vigneshvar Chandrasekaran, Avin Muthuramalingam, Karthick Subramanian   +2 more
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Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening   +12 more
doaj   +1 more source

Involvement of the TNF-α/SATB2 axis in the induced apoptosis and inhibited autophagy of osteoblasts by the antipsychotic Risperidone

Molecular Medicine, 2022
Background Risperidone, an atypical antipsychotic, impedes serotonin and dopamine receptor systems. Meanwhile, tumor necrosis factor-α (TNF-α) is known to participate in regulating osteoblast functions.
Shuyao Zhang, Wei He, Aiguo Li, Chengkuan Zhao, Yun Chen, Chengcheng Xu, Qiuzhen Zhang, Danling Zheng, Meini Chen, Haixiong Miao, Yihui Huang   +10 more
doaj   +1 more source

A single blind comparative clinical study of the effects of chlorpromazine and risperidone on positive and negative symptoms in patients of schizophrenia

Indian Journal of Psychological Medicine, 2011
Objectives: The present study was undertaken to test the comparative efficacy of chlorpromazine and risperidone in patients of schizophrenia in a tertiary care hospital of Maharashtra.
Amrita Prakash Singam, Abhishek Mamarde, Prakash B Behere   +2 more
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A prospective study to evaluate the effect of CYP2D6 polymorphism on plasma level of risperidone and its metabolite in North Indian patients with schizophrenia

Indian Journal of Psychological Medicine, 2018
Background: Risperidone is one of commonly utilized antipsychotic in clinical practice. Various metabolizing enzymes effect the plasma levels of risperidone and its active metabolite and thus its clinical efficacy.
Bir S Chavan, Gurjit Kaur, Deepti Gupta, Jitender Aneja   +3 more
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CYP2D6 Genotype-Based Dose Recommendations for Risperidone in Asian People

Frontiers in Pharmacology, 2020
The aim of this study was to provide dose recommendations for risperidone in Asian people based on cytochrome P450 enzyme CYP2D6 genotype. First, we investigated the influence of CYP2D6 polymorphism on the pharmacokinetics of risperidone in Chinese ...
Yuanxia Cui, Yuanxia Cui, Hao Yan, Hao Yan, Yi Su, Yi Su, Lifang Wang, Lifang Wang, Tianlan Lu, Tianlan Lu, Dai Zhang, Dai Zhang, Weihua Yue, Weihua Yue, Weihua Yue   +14 more
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The Steady-State Comparative Bioavailability of Intramuscular Risperidone ISM and Oral Risperidone: An Open-Label, One-Sequence Study

Drug Design, Development and Therapy, 2021
David P Walling,1 Howard A Hassman,2 Lourdes Anta,3 Lourdes Ochoa,4 Ignacio Ayani,3 Javier Martínez,3 Ibon Gutierro4 1Collaborative Neuroscience Network, LLC Garden Grove, Garden Grove, CA, USA; 2Hassman Research Institute, Berlin, NJ, USA; 3Medical ...
Walling DP, Hassman HA, Anta L, Ochoa L, Ayani I, Martínez J, Gutierro I   +6 more
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Relapse in patients with schizophrenia: a comparison between risperidone and haloperidol [PDF]

Brazilian Journal of Psychiatry, 2003
OBJECTIVES: To compare rates of rehospitalization and time to relapse in risperidone vs. haloperidol-treated schizophrenic patients discharged from the hospital. METHODS: Randomized controlled trial comparing risperidone and haloperidol regarding relapse
Eduardo Pondé de Sena, Rogério Santos-Jesus, Ângela Miranda-Scippa, Lucas de Castro Quarantini, Irismar Reis de Oliveira   +4 more
doaj   +1 more source