Antibiotic Resistance Mechanisms Inform Discovery: Identification and Characterization of a Novel Amycolatopsis Strain Producing Ristocetin [PDF]
Discovering new antibiotics is a major scientific challenge, made increasingly urgent by the continued development of resistance in bacterial pathogens.
Andrew W. Truman +5 more
semanticscholar +6 more sources
BACKGROUND Injury to the blood-brain barrier exposes endothelium rich in von Willebrand factor (vWF), which may play a role in altered platelet aggregation following traumatic brain injury (TBI).
Lucy Z Kornblith, Anamaria J Robles
exaly +2 more sources
Bleeding because of impaired platelet function is a major side effect of the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib. We quantitatively assessed ristocetin-induced platelet aggregation (RIPA) in 64 patients with chronic lymphocytic leukemia ...
Alexander Egle
exaly +2 more sources
The draft genome sequence of a ristocetin-producing Amycolatopsis strain (sp. MJM2582) isolated in South Korea is reported here. This strain has a genome of approximately 8.9 Mb containing 7,933 predicted genes, including the ristocetin cluster and 32 ...
Min Jung Kwun +5 more
openalex +2 more sources
Thrombocytosis and bleeding in myeloproliferative neoplasms: exploring clinical diversity and risk of acquired von Willebrand syndrome—insights from a UK center [PDF]
Background: Myeloproliferative neoplasms (MPNs) represent a group of blood disorders characterized by myeloid cell proliferation and an associated increased risk of thrombosis and bleeding.
Giulia Simini +8 more
doaj +2 more sources
Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor [PDF]
BS Coller +3 more
semanticscholar +3 more sources
A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen [PDF]
CG Ruan +4 more
semanticscholar +4 more sources
Limitations of the ristocetin cofactor assay in measurement of von Willebrand factor function
V. Flood +9 more
exaly +2 more sources

