Results 101 to 110 of about 13,243 (286)

Enhanced platelet adhesion in essential thrombocythemia after in vitro activation [PDF]

, 2010
Objective: Essential thrombocythemia (ET) is a chronic myeloproliferative disorder characterized by elevated platelet counts and increased risk of thrombosis.
Andreas C. Eriksson, Kourosh Lotfi, Per A. Whiss   +2 more
core  

von Willebrand's disease: a report from a meeting in the Åland islands [PDF]

, 2012
von Willebrand's disease (VWD) is probably the most common bleeding disorder, with some studies indicating that up to 1% of the population may have the condition.
Bergamaschini, Berntorp, Berntorp, Berntorp, Berntorp, Berntorp, Borel-Derlon, Bowen, Dean, Dunkley, Federici, Federici, Flood, Franchini, Goodeve, Hyatt, Iorio, Klenk, Laffan, Larsson, Lassila, Lethagen, Mannucci, Mannucci, Matsui, McGrath, Nichols, Nilsson, Pasi, Rodeghiero, Rodeghiero, Ruggeri, Ruggeri, Sadler, Sadler, Sarji, Soulier, Stray-Pedersen, Sweeney, Titani, Tosetto, Von Willebrand, Von Willebrand, Von Willebrand, Williams, Witmer, Zhang   +46 more
core   +1 more source

Enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines using ristocetin macrocyclic glycopeptide antibiotics CSP

Journal of Taibah University for Science, 2020
The enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines is described on Chirobiotc R column (150 ×4.6 mm, 5.0 µm). Two eluents used were methanol–acetonitrile-water-triethyl amine in the ratio of 70:10:20:0.1 (I) and
Zeid A. ALOthman, Abdullah G. ALanazi, Imran Ali   +2 more
doaj   +1 more source

Identification of one novel pathogenic ITGB3 mutation and two known mutations in two Chinese pedigrees with hereditary Glanzmann thrombasthenia

Platelets, 2020
Glanzmann thrombasthenia (GT) is an inherited disorder of platelet aggregation resulting from quantitative and/or qualitative abnormalities of the glycoprotein IIb/IIIa complex.
Zhengjing Lu, Lauriane Nikuze, Zhoulin Zhong, Fang Li, Fuyong Zhang, Kairong Liang, Manlv Wei, Hongying Wei   +7 more
doaj   +1 more source

The N-terminal domain of human GATA1 prevents dyserythropoietic anemia and megakaryocyte dysplasia in vivo [PDF]

, 2015
We describe a child with dyserythropoietic anemia, thrombocytosis, functional platelet defect, and megakaryocyte dysplasia. We show that (i) this constellation of hematopoietic abnormalities was due to a germline mutation within the 5′ untranslated ...
Czader, Magdalena, Nalepa, Grzegorz, Temm, Constance, Zucker, Jacob   +3 more
core   +2 more sources

Successful treatment of refractory gastrointestinal bleeding by systemic (oral) ankaferd blood stopper in a patient with Glanzmann thrombasthenia [PDF]

, 2015
Background: Glanzmann Thrombasthenia (GT) is a genetic platelet dysfunction and a life threatening disease. Ankaferd Blood Stopper (ABS) is a topical hemostatic agent of herbal origin which has been recently made available for clinical use.
Doğu, Mehmet Hilmi, Hacıoğlu, Sibel Kabukçu, Keskin, Ali, Sarı, İsmail   +3 more
core   +2 more sources

Assessment of platelet function on the routine coagulation analyzer Sysmex CS-2000i

Platelets, 2018
Background: Light transmission aggregometry (LTA) is considered as the gold standard for testing platelet function in the setting of both platelet disorders suspicion and response to antiplatelet therapy evaluation.
Corinne Frère, Katsushi Kobayashi, Claire Dunois, Jean Amiral, Pierre-Emmanuel Morange, Marie-Christine Alessi   +5 more
doaj   +1 more source

Influence of hyperinsulinemic – hypoglycemic clamp on induced platelet aggregation, activity of physiological anticoagulants and von Willebrand factor in patients with type I diabetes

Сахарный диабет, 2018
Background. Intensive glycaemic control in patients with type 1 diabetes may lead to hypoglycaemia and thus increase the risk of cardiovascular and cerebrovascular events.
Iwona R. Jarek-Martynowa, Mikhail Y. Martynov, Karina G. Sarkisova, Ekaterina O. Koksharova, Ekaterina E. Mishina, Albina N. Yasamanova, Marina V. Shestakova   +6 more
doaj   +1 more source

Newer agents in antiplatelet therapy: a review. [PDF]

, 2012
Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke.
Holinstat, Michael, Yeung, Jennifer
core   +3 more sources

Bernard Soulier Syndrome: Presenting As High-grade Fever In A Young Male

Journal of Bahria University Medical and Dental College, 2019
Bernard-Soulier syndrome (BSS) is a rare inherited disorder of blood clotting (coagulation). They may be life-threatening and demand immediate attention.
Syed Parvez Asghar, Rida Ali Asghar, Syed Sajid Abbas Jaffari, Zehra Akhtar, Naveed Siddique   +4 more
doaj   +1 more source