Results 11 to 20 of about 13,243 (286)

Structure of Ristocetin A [PDF]

open access: greenProceedings of the National Academy of Sciences, 1972
Acid hydrolysis of ristocein A yields a number of amino acids of unusual structure. One set of diastereoisomeric pairs has a molecular weight of 362 and an empirical formula of C 17 H 18 N 2 O 7 .
J. R. Fehlner   +3 more
openaire   +4 more sources

Studies on the Mechanism of Ristocetin-Induced Platelet Agglutination [PDF]

open access: bronzeJournal of Clinical Investigation, 1977
The mechanism by which ristocetin induces platelet agglutination in the presence of the von Willebrand factor was studied by chemically altering ristocetin and a similar antibiotic, vancomycin, by reaction with a water-soluble carbodiimide in the presence of glycine methyl ester at pH 4.75. Altering ristocetin's phenolic groups (which are thought to be
Harvey R. Gralnick, Barry S. Coller
openaire   +4 more sources

A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry [PDF]

open access: bronzeJournal of Thrombosis and Haemostasis, 2008
D. Chen   +6 more
exaly   +4 more sources

Ristocetin Interactions With Human Platelet Membranes [PDF]

open access: bronzeThrombosis and Haemostasis, 1981
Ristocetin was coupled to CH-Sepharose-4B by coupling with l-ethyl-3-(3 dimethyl-aminopropyl) carbodiimide. The resulting adduct was treated with 1M hydroxylamine pH7.0, for 4 hours at 22°C to remove carbodiimide complexes of the phenolic hydroxyl groups of ristocetin. This ristocetin affinity column was found to strongly bind acetyl-D-alayl- D-alanine,
J Feldman   +3 more
openaire   +3 more sources

Draft Genome Sequence of Ristocetin-Producing Strain Amycolatopsis sp. Strain MJM2582 Isolated in South Korea

open access: goldGenome Announcements, 2014
The draft genome sequence of a ristocetin-producing Amycolatopsis strain (sp. MJM2582) isolated in South Korea is reported here. This strain has a genome of approximately 8.9 Mb containing 7,933 predicted genes, including the ristocetin cluster and 32 ...
M. Kwun   +5 more
semanticscholar   +2 more sources

A comparative study between the Chrono-log 700 and the Sysmex CS-2100i analyzers for assessing ristocetin cofactor activity in patients with von Willebrand disease

open access: goldJournal of Laboratory Medicine
A variety of methods are currently used to measure von Willebrand factor (VWF) activity, but still the VWF ristocetin cofactor (VWF:RCo) assay using the manual aggregometry technique is the reference method, even having high inter-laboratory variability.
Boulassel Mohamed-Rachid   +6 more
doaj   +2 more sources

Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure

open access: goldResearch and Practice in Thrombosis and Haemostasis, 2022
Background Von Willebrand disease (VWD) is a common inherited bleeding disorder, however the diagnosis can be complicated by a subjective bleeding history and issues with some current von Willebrand factor (VWF) laboratory assays.
Pamela A. Christopherson   +6 more
doaj   +2 more sources

Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication

open access: yesPharmaceuticals, 2021
The protracted global COVID-19 pandemic urges the development of new drugs against the causative agent SARS-CoV-2. The clinically used glycopeptide antibiotic, teicoplanin, emerged as a potential antiviral, and its efficacy was improved with lipophilic ...
Ilona Bereczki   +20 more
doaj   +1 more source

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