Antibiotic resistance mechanisms inform discovery: identification and characterization of a novel amycolatopsis strain producing ristocetin. [PDF]
Discovering new antibiotics is a major scientific challenge, made increasingly urgent by the continued development of resistance in bacterial pathogens.
Cheng, Jinhua +5 more
core +4 more sources
Enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines using ristocetin macrocyclic glycopeptide antibiotics CSP [PDF]
The enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines is described on Chirobiotc R column (150 ×4.6 mm, 5.0 µm). Two eluents used were methanol–acetonitrile-water-triethyl amine in the ratio of 70:10:20:0.1 (I) and
Zeid A. ALOthman +2 more
doaj +2 more sources
Letter: Ristocetin-induced platelet aggregation [PDF]
B G, Firkin +5 more
openaire +4 more sources
How Trustworthy is Light Transmittance Platelet Aggregometry With Low Platelet Count Samples? Insights From Test Replicates and Retrospective Analysis of Several Decades of Diagnostic Samples. [PDF]
ABSTRACT Introduction Light transmission platelet aggregometry (LTA) is useful to diagnose platelet function disorders (PFD). We evaluated the precision and reproducibility of LTA with low platelet count platelet‐rich plasma (LPRP). Methods LPRP maximal aggregation (MA) precision for informative agonists and LTA reproducibility were assessed using ...
Hayward CPM +3 more
europepmc +2 more sources
Management of von Willebrand Disease With a Factor VIII-Poor von Willebrand Factor Concentrate: Results From the Paediatric Cohort of a Prospective Observational Post-Marketing Study. [PDF]
ABSTRACT Introduction Although clinical experience of a triple‐secured, plasma‐derived, von Willebrand factor (pdVWF), almost devoid of Factor VIII (FVIII) in adults with von Willebrand disease (VWD), is widely reported, its use in children is less documented.
Goudemand J +10 more
europepmc +2 more sources
Glanzmann thrombasthenia (GT) is a rare autosomal recessive inherited platelet disorder occurring frequently in populations with high incidence of consanguineous marriages.
Muhammad Younus Jamal Siddiqi +6 more
doaj +1 more source
Measurement of teicoplanin by liquid chromatography-tandem mass spectrometry:development of a novel method [PDF]
Teicoplanin is an antibiotic used for the treatment of endocarditis, osteomyelitis, septic arthritis and methicillin-resistant Staphylococcus aureus. Teicoplanin is emerging as a suitable alternative antibiotic to vancomycin, where their trough serum ...
Bailey, Lisa M +5 more
core +1 more source
Diagnosis of von Willebrand disease in Argentina: a single institution experience [PDF]
von Willebrand disease (VWD) is the most common autosomal bleeding disorder, mostlyinherited as dominant trait. VWD is due to deficiency/abnormality of von Willebrand factor (VWF).
Blanco, Alicia Noemi +5 more
core +1 more source
Laboratory Diagnosis of von Willebrand's Disease
von Willebrand's disease (vWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (vWF). vWF is a multimeric adhesive protein that plays an important role in primary hemostasis by promoting ...
Mansyur Arif
doaj +1 more source
Einfluss niedermolekularer Hydroxyethylstärke unterschiedlicher Ausgangssubstanz auf die Hämostase [PDF]
Die Infusion von Hydroxyethylstärke (HES) kann potentiell über verschiedene Mechanismen die Hämostase beeinflussen. Aufgrund der Variabilität des HES- Moleküls steht eine Vielfalt an Präparaten mit unterschiedlichen pharmakologischen und -kinetischen ...
Karopka,Susanne, Zeiler, Thomas (Dr.)
core +1 more source

