Results 221 to 230 of about 13,243 (286)

Whole blood ristocetin-activated platelet impedance aggregometry (Multiplate) for the rapid detection of Von Willebrand disease

Thrombosis and Haemostasis, 2017
David E Schmidt, Jacob O Odeberg
exaly   +2 more sources

Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method

Haemophilia, 2013
N. Cabrera, A. Moret, P. Caunedo, A. Cid, V. Vila, F. España, J. Aznar   +6 more
exaly   +2 more sources

Diazo Transfer−Click Reaction Route to New, Lipophilic Teicoplanin and Ristocetin Aglycon Derivatives with High Antibacterial and Anti-influenza Virus Activity: An Aggregation and Receptor Binding Study

Journal of Medicinal Chemistry, 2009
Gyula Batta, Ferenc Sztaricskai, Eszter Ostorházi   +2 more
exaly   +2 more sources

Total Synthesis of the Ristocetin Aglycon

Journal of the American Chemical Society, 2004
The first total synthesis of the ristocetin aglycon is described employing a modular and highly convergent strategy. An effective 12-step (12% overall) synthesis of the ABCD ring system 3 from its amino acid subunits sequentially features an intramolecular aromatic nucleophilic substitution reaction for formation of the diaryl ether and closure of the ...
Dale L Boger
exaly   +4 more sources

Efficacy and Safety of the Factor VIII/von Willebrand Factor Concentrate, Haemate-P/Humate-P: Ristocetin Cofactor Unit Dosing in Patients with von Willebrand Disease

Thrombosis and Haemostasis, 2002
D. Lillicrap, Man-Chiu Poon, Irwin Walker, F. Xie, B. A. Schwartz   +4 more
exaly   +2 more sources

Ristocetin and Ristocetin-Neomycin for Preoperative Preparation of the Colon

Archives of Surgery, 1958
Interest in antibacterial agents for preoperative preparation of the bowel has stimulated us to evaluate new agents by standardized techniques which permit comparisons of different agents.1,2,7Ristocetin, isolated from the actinomycete Nocardia lurida recovered from a Colorado soil sample, has been reported to be particularly effective against ...
Isidore Cohn, Alfred B. Longacre
openaire   +3 more sources

Binding of Ristocetin to Platelets [PDF]

Thrombosis and Haemostasis, 1979
Ristocetin induces platelet agglutination in the presence of von Willebrand factor (VIIIR:WF), part of the factor VIII complex. The role of ristocetin in platelet agglutination is not yet. Clear. To follow the interaction of ristocetin with platelets and/or VIIIR:WF, ristocetin was labelled with[3H] by reductive methylation.
E.F. Lüscher, C.S.P. Jenkins, K.J. Clemetson   +2 more
openaire   +1 more source

On the interaction between ristocetin and the ristocetin cofactor (RCOF)

Thrombosis Research, 1977
Abstract The induction of platelet aggregation by the antibiotic ristocet in requires the participation of a plasma factor, Ristocetin CoFactor (RCoF), which is deficient in patients with vonWillebrand's disease. Although it has been shown that ristocetin precipitates fibrinogen, its interaction with RCoF remains obscure.
David Green, Michael Floyd, William J. Burns   +2 more
openaire   +3 more sources

The biosynthesis of ristocetin

Journal of the Chemical Society, Chemical Communications, 1983
In the biosynthesis of ristocetin by Nocardia Iurida it has been shown that m,m′-dihydroxyphenylglycine and p-methyl-m,m′- dihydroxyphenylglycine can be derived from acetic acid, whereas p-hydroxyphenylglycine and β-hydroxytyrosine are derived from tyrosine.
Dudley H. Williams, Stephen J. Hammond, Robert V. Nielsen   +2 more
openaire   +2 more sources

Actions of ristocetin on platelets

American Journal of Hematology, 1976
AbstractThe absence of ristocetin‐induced platelet aggregation appears to correlate with the platelet defect in von Willebrand's disease, suggesting that this reaction mimics a physiological process. The effect of ristocetin on plasma and on the residual levels of the von Willebrand factor (vWF), Factor VIII procoagulant activity, and Factor VIII ...
J. Koutts, Lyne Stott B. Sc, Barry G. Firkin   +2 more
openaire   +2 more sources