Results 231 to 240 of about 13,399 (295)
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Ristocetin and Ristocetin-Neomycin for Preoperative Preparation of the Colon
Archives of Surgery, 1958Interest in antibacterial agents for preoperative preparation of the bowel has stimulated us to evaluate new agents by standardized techniques which permit comparisons of different agents.1,2,7Ristocetin, isolated from the actinomycete Nocardia lurida recovered from a Colorado soil sample, has been reported to be particularly effective against ...
I, COHN, A B, LONGACRE
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On the interaction between ristocetin and the ristocetin cofactor (RCOF)
Thrombosis Research, 1977Abstract The induction of platelet aggregation by the antibiotic ristocet in requires the participation of a plasma factor, Ristocetin CoFactor (RCoF), which is deficient in patients with vonWillebrand's disease. Although it has been shown that ristocetin precipitates fibrinogen, its interaction with RCoF remains obscure.
M, Floyd, W, Burns, D, Green
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Evaluation of Ristocetin–Willebrand Factor Assay and Ristocetin-induced Platelet Aggregation
American Journal of Clinical Pathology, 1975Normal subjects, patients with various bleeding disorders, and patients with von Willebrand's disease were studied. All patients with von Willebrand's disease had decreased levels of ristocetin-Willebrand factor (range, 0 to 41%) as compared with all other subjects (range, 79 to 202%). Ristocetin-induced platelet aggregation of platelet-rich plasma was
J D, Olson +4 more
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Actions of ristocetin on platelets
American Journal of Hematology, 1976AbstractThe absence of ristocetin‐induced platelet aggregation appears to correlate with the platelet defect in von Willebrand's disease, suggesting that this reaction mimics a physiological process. The effect of ristocetin on plasma and on the residual levels of the von Willebrand factor (vWF), Factor VIII procoagulant activity, and Factor VIII ...
J, Koutts, L, Stott, B G, Firkin
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Ristocetin-induced aggregation of canine platelets
Thrombosis Research, 1980Abstract Both canine plasma and canine platelets have been reported to be unreactive in the ristocetin-induced platelet aggregation reaction that is commonly used to study the platelet-von Willebrand factor interaction. Because canine plasma was recently found to have ristocetin cofactor (RCF) activity with human platelets, we studied the RCF ...
L A, Leis +3 more
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STAPHYLOCOCCIC ENDOCARDITIS TREATED WITH RISTOCETIN
Journal of the American Medical Association, 1958The treatment of endocarditis caused by Staphylococcus (Micrococcus) pyogenes var. aureus has become a challenging problem; therefore, two patients successfully treated with a new antibiotic agent, ristocetin, are reported on here. In these two patients, the infections were acquired in hospitals and, as might be expected, the staphylococci were ...
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The biosynthesis of ristocetin
Journal of the Chemical Society, Chemical Communications, 1983In the biosynthesis of ristocetin by Nocardia Iurida it has been shown that m,m′-dihydroxyphenylglycine and p-methyl-m,m′- dihydroxyphenylglycine can be derived from acetic acid, whereas p-hydroxyphenylglycine and β-hydroxytyrosine are derived from tyrosine.
Stephen J. Hammond +2 more
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Willebrand Factor and Ristocetin I. MECHANISM OF RISTOCETIN‐INDUCED PLATELET AGGREGATION
British Journal of Haematology, 1974Summary. Ristocetin induces aggregation of normal platelet‐rich plasma over a wide range of concentrations. Low doses induce a biphasic response of which the first wave is not mediated by ADP and proceeds without the initial platelet shape change. The absence of aggregation in von Willebrand's disease results from the lack of a component, Willebrand ...
C S, Jenkins +3 more
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Ristocetin induces platelet aggregation: a morphological demonstration
British Journal of Haematology, 1988Changes in the morphology of human platelets induced by ristocetin in platelet‐rich plasma (PRP) have been analysed at the ultrastructural level by means of a tannic acid procedure. Studies were also undertaken to measure the release of serotonin. Modifications of the aggregation tests induced by apyrase, a monoclonal antibody (Mab) to GPIIb/ IIIa and ...
G, Escolar +5 more
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