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Purification of Ristocetin Willebrand Factor (RWF) [PDF]
A component required for the ristocetin-induced aggregation of platelets was isolated in yields of 20-30% from pooled human and porcine plasma by cryoethanol concentration of the RWF, after removal of the vitamin K dependent coagulation factors on barium citrate.
K. G. Mann +4 more
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Thrombosis Research, 1976
Abstract Albumin, fibrinogen and Haemaccel inhibit ristocetin-induced platelet aggregation by binding ristocetin. Increasing the ristocetin concentration can overcome this inhibition. Ristocetin precipitates albumin, fibrinogen, and Haemaccel. Precipitation is dependent on both the protein and the ristocetin concentration.
Edward P. Kirby +3 more
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Abstract Albumin, fibrinogen and Haemaccel inhibit ristocetin-induced platelet aggregation by binding ristocetin. Increasing the ristocetin concentration can overcome this inhibition. Ristocetin precipitates albumin, fibrinogen, and Haemaccel. Precipitation is dependent on both the protein and the ristocetin concentration.
Edward P. Kirby +3 more
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Platelet Responses to Ristocetin in Von Willebrand's Disease
Scandinavian Journal of Haematology, 1974Studies of the aggregations of platelets in response to ristocetin have been carried out in normal subjects and in 21 patients with von Willebrand's disease. These demonstrate a wide range of patterns of response to ristocetin in von Willebrand's disease, the responses depending on a plasma factor labile at room temperature.
Sheila Cooke +2 more
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Ristocetin, a laboratory and clinical evaluation in children
The Journal of Pediatrics, 1960Summary 1. The recommended dose of ristocetin for children is 25 mg. per kilogram every 12 hours. Adequate serum levels are produced by this dosage by either the intravenous or intramuscular route. 2. The intravenous preparation of ristocetin can be administered safely intramuscularly if 1 mg. of hydrocortisone per 100 mg. of ristocetin is added
Richard Koch, Charles P. Dries
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Further Studies of the Interaction between Ristocetin and Fibrinogen
Pathophysiology of Haemostasis and Thrombosis, 1976Fibrinogen (FG) precipitation by ristocetin is enhanced by lowering the temperature to 4 °C. The precipitate has similar properties to an acquired cryofibrinogen being resolubilised on rewarming to 37 °C, and the process of precipitation and resolubilisation can be repeated indefinitely by lowering and raising the temperature. Other plasma proteins are
A.T.W. Goh, B.G. Firkin
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Iodination of vancomycin, ristocetin A, and ristocetin pseudoaglycon [PDF]
R. Kannan +4 more
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Lithium inhibition of ristocetin-induced fibrinogen precipitation
Thrombosis Research, 1978We have recently shown that ristocetin-induced platelet aggregation can be inhibited by lithium, perhaps by the involvement of a plasma factor, possibly fibrinogen (1). 5esides inducing platelet aggregation, ristocetin will also precipitate fibrinogen from human plasma (2). Using a rapid slide testassay (3).
P.C. Hayes, L.N.McF. Hargreaves
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Ristocetin-Induced Platelet Aggregation (RIPA) and RIPA Mixing Studies.
Methods in molecular biology, 2017J. Frontroth, E. Favaloro
semanticscholar +1 more source
Laboratory Testing for von Willebrand Factor Ristocetin Cofactor (VWF:RCo).
Methods in molecular biology, 2017S. Mohammed, E. Favaloro
semanticscholar +1 more source

