Results 21 to 30 of about 9,310 (270)

A few atoms make the difference: Synthetic, CD, NMR and computational studies on antiviral and antibacterial activities of glycopeptide antibiotic aglycon derivatives [PDF]

, 2018
K
Batta, Gyula, Bereczki, Ilona, Borbás, Anikó, Fizil, Ádám, Herczegh, Pál, Komáromi, István, Kurtán, Tibor, Mándi, Attila, Naesens, Lieve, Ostorházi, Eszter, Rozgonyi, Ferenc, Rőth, Erzsébet, Sipos, Attila, Sztaricskai, Ferenc, Vanderlinden, Evelien   +14 more
core   +1 more source

A New Binding Assay of von Willebrand Factor and Glycoprotein Ib Using Solid-Phase Biotinylated Platelets

Journal of Pharmacological Sciences, 2008
To obtain compounds that inhibit the interaction of von Willebrand factor (vWF) and glycoprotein (GP) Ib, a novel binding assay was established. The binding of fixed platelets to vWF-R497 mutant was quantified by a solid phase assay. In this assay, fixed
Kenji Hayata, Takayuki Nakayama, Tadashi Matsushita, Katsuichi Sakano   +3 more
doaj   +1 more source

Draft Genome Sequence of Amycolatopsis lurida NRRL 2430, Producer of the Glycopeptide Family Antibiotic Ristocetin. [PDF]

, 2014
We report here the first draft genome sequence for Amycolatopsis lurida NRRL 2430, the producer of the glycopeptide antibiotic ristocetin. The 9-Mbp genome is predicted to harbor 8,143 genes, including those belonging to the ristocetin biosynthesis ...
Hong, Hee-Jeon, Kwun, Min Jung
core   +3 more sources

Laboratory diagnosis and monitoring of desmopressin treatment of von Willebrand’s disease by flow cytometry

Haematologica, 2007
Background and Objectives von Willebrand’s disease (VWD) is a heterogeneous bleeding disorder caused by quantitative or qualitative defects in von Willebrand factor (VWF). The diagnosis of VWD requires several laboratory tests.
Silvia Giannini, Anna Maria Mezzasoma, Mario Leone, Paolo Gresele   +3 more
doaj   +1 more source

Laboratory aspects of von Willebrand disease: test repertoire and options for activity assays and genetic analysis [PDF]

, 2014
The deficiency or abnormal function of von Willebrand factor (VWF) causes von Willebrand disease (VWD), the most frequent inherited bleeding disorder. The laboratory diagnosis of VWD can be difficult as the disease is heterogeneous and an array of assays
Castaman, G., Goodeve, A., Hillarp, A.
core   +1 more source

Assessment of light transmission aggregometry on the routine coagulation analyzer Sysmex CS-2500 using CE-marked agonists from Hyphen Biomed

Platelets, 2019
Light transmission aggregometry (LTA) is still considered as the “gold standard” for platelet function assessment but, as acompletely manual technology, it is labour intensive.
V.-E. Bret, B. Pougault, A. Guy, S. Castet, Y. Huguenin, X. Pillois, C. James, M. Fiore   +7 more
doaj   +1 more source

MISDIAGNOSIS OF ACQUIRED VON WILLEBRAND DISEASE

Hematology, Transfusion and Cell Therapy, 2023
Introduction: The diagnosis of acquired von willebrand disease (VWD) is a challenge for laboratory investigation. Alloantibodies may present different kinetics of FVW neutralization and thus generate inconclusive results.
AP Francisco, SC Huber, AP Verissimo, JMA Bizzacci, SAL Montalvão   +4 more
doaj   +1 more source

Large-scale purification of factor VIII by affinity chromatography: optimization of process parameters [PDF]

, 1990
The optimization of a new process for the extraction of human coagulation factor VIII (FVIII) from plasma with the tailor-made affinity matrix dimethylaminopropylcarbamylpentyl-Sepharose CL-4B (C3---C5 matrix) is described.
Bantjes, Adriaan, Beugeling, Tom, Booy, Marcel P.W.M. te, Faber, Anita, Jonge, Egge de, König, Boudewijn W., Over, Jan, Riethorst, Waander, Wolterink, Ernst P.   +8 more
core   +10 more sources

Evaluation of an automated light transmission aggregometry

Platelets, 2017
Light transmission aggregometry (LTA) is the “gold standard” for platelet function assessment, but it is time-consuming and labor intensive. Recently, an automated platelet aggregation method has been developed on a routine coagulation analyzer (Sysmex ...
Li-qin Ling, Juan Liao, Qian Niu, Xia Wang, Jin Jia, Cheng-hua Zuo, Hong Jiang, Jing Zhou   +7 more
doaj   +1 more source

Closing the gap – detection of clinically relevant von Willebrand disease in emergency settings through an improved algorithm based on rotational Thromboelastometry

BMC Anesthesiology, 2019
Background Hemorrhage and blood loss are still among the main causes of preventable death. Global hemostatic assays are useful point-of-care test (POCT) devices to rapidly detect cumulative effects of plasma factors and platelets on coagulation ...
H.-G. Topf, E. R. Strasser, G. Breuer, W. Rascher, M. Rauh, F. B. Fahlbusch   +5 more
doaj   +1 more source