Results 21 to 30 of about 13,243 (286)

Platelet function in overt hypothyroidism

Journal of Applied Hematology, 2021
BACKGROUND: Hypothyroidism is associated with a shift of the hemostatic system to a hypocoagulable state and inhibited platelet function. However, previous studies did not consider the different degrees of response to thyroxine treatment and its effect ...
Abeer Khalid Al-Ghumlas, Aishah Ali Ekhzaimy, Abdel Galil Mohammad Abdel Gader   +2 more
doaj   +1 more source

Synthesis of the F-O-G fragment of ristocetin A via ruthenium-promoted intermolecular SNAr reaction

ARKIVOC, 2002
Anthony J. Pearson, Avdhoot D. Velankar, Jung-Nyoung Heo   +2 more
doaj   +3 more sources

Bleeding Complications in JAK2-Variant Essential Thrombocythemia: A Revisit in 2025. [PDF]

EJHaem
ABSTRACT Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterised by sustained thrombocytosis. Paradoxically, bleeding complications remain an under‐recognised clinical challenge. Compared with CALR‐mutated patients, those harbouring the JAK2‐V617F variant appear more prone to haemorrhage.
Gurumurthy G, Gurumurthy S, Somervaille TCP, Falanga A, Thachil J.   +4 more
europepmc   +2 more sources

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Bernard Soulier syndrome: A case report from Pakistan

Clinical Case Reports, 2023
Key Clinical Message Bernard Soulier Syndrome should be suspected in patients with bleeding disorder symptoms and significant family history, where consanguineous marriages are common.
Iqra Effendi, Ahsan Nadeem, Sara Sarfraz, Mubasshar Shahid, Minaam Farooq, Ayush Anand   +5 more
doaj   +1 more source

Influencing Factors and Differences in Born Aggregometry in Specialized Hemostaseological Centers: Results of a Multicenter Laboratory Comparison

TH Open, 2022
Introduction Light transmission aggregometry (LTA) is regarded as the gold standard in platelet function diagnostics. However, there is a relevant degree of interlaboratory variability in practical applications.
Thorsten Kaiser, Karin Liebscher, Ute Scholz, Christian Pfrepper, Jeffrey Netto, Tim Drogies, Oliver Tiebel, Ralf Knöfler, Michael Krause   +8 more
doaj   +1 more source

Structure of ristocetin A in complex with a bacterial cell-wall mimetic. [PDF]

Acta Crystallographica Section D: Biological Crystallography, 2009
V. Nahoum, Sherri Spector, P. Loll
semanticscholar   +2 more sources

THE CLINICAL PICTURE AND LABORATORY WORK-UP OF GLANZMANN THROMBASTHENIA

Hematology, Transfusion and Cell Therapy, 2021
Case report: We present the clinical picture and laboratory work-up of Glanzmann thrombasthenia, based on a group of 7 patients. Bleeding history was significant in all patients and included both mucosal and postsurgery bleeds.
Joanna Zdziarska, Teresa Iwaniec, Tomasz Sacha, Ewa Wypasek   +3 more
doaj   +1 more source

Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant in pseudothrombocytopenia

Platelets, 2020
MgSO4 is effective in preventing spontaneous in vitro platelet agglutination in anticoagulant-induced pseudothrombocytopenia (PTCP). In order to learn more about its potential as an in vitro anticoagulant, platelets from MgSO4-anticoagulated blood were ...
Steffen Mannuß, Peter Schuff-Werner, Katrin Dreißiger, Christine Burstein   +3 more
doaj   +1 more source

Glanzmann Thrombasthenia in Pakistani Patients: Identification of 7 Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3

Cells, 2023
Glanzmann thrombasthenia (GT) is a rare autosomal recessive inherited platelet disorder occurring frequently in populations with high incidence of consanguineous marriages.
Muhammad Younus Jamal Siddiqi, Doris Boeckelmann, Arshi Naz, Ayisha Imran, Shariq Ahmed, Akbar Najmuddin, Barbara Zieger   +6 more
doaj   +1 more source