Results 31 to 40 of about 9,310 (270)
The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding. [PDF]
, 2016 Multimerin 1 (MMRN1) is a massive, homopolymeric protein that is stored in platelets and endothelial cells for activation-induced release. In vitro, MMRN1 binds to the outer surfaces of activated platelets and endothelial cells, the extracellular matrix (
Bihan, Dominique +7 more
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Acquired von Willebrand disease as a cause of recurrent mucocutaneous bleeding in primary thrombocythemia: Relationship with platelet count [PDF]
, 1994 We present a 4-year follow-up of a 42-year-old patient with primary thrombocythemia whose clinical course was complicated by two major mucocutaneous bleeding episodes.
Genderen, P.J.J. (Perry) van +3 more
core +1 more source
Platelet Dysfunction in Patients with Chronic Myeloid Leukemia: Does Imatinib Mesylate Improve It?
Turkish Journal of Hematology, 2016 INTRODUCTION: The aim of this study was to investigate the effects of imatinib mesylate on platelet aggregation and adenosine triphosphate (ATP) release in chronic myeloid leukemia patients. METHODS: Platelet aggregation and ATP release induced by 5.0 mM
Olga Meltem Akay +2 more
doaj +1 more source
Von Willebrand disease type 2B with a novel mutation in the VWF gene
Annals of Saudi Medicine, 2021 We report a 38-year-old woman who presented with a subdural hematoma after minor facial trauma in a stressful situation. The laboratory data showed a subnormal platelet count (166×109/L), VWF:RCo activity was 45% and VWF:Ag was 53% with a VWF:RCo/VWF Ag ...
Mohammed Abdullah Jeraiby +4 more
doaj +1 more source
Recent advances in the analysis of antibiotics by capillary electrophoresis [PDF]
, 2006 In this review, the main aspects related to the separation of different groups of antibiotics by CE as well as the different applications reported in the literature from the beginning 2003 till May 2005 will be provided to the readers.
García Ruiz, Carmen +1 more
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The aptamer BT200 blocks von Willebrand factor and platelet function in blood of stroke patients
Scientific Reports, 2021 The effect of conventional anti-platelet agents is limited in secondary stroke prevention, and their effects are blunted under high shear stress in the presence of increased levels of circulating von Willebrand factor (VWF). VWF is critically involved in
Katarina D. Kovacevic +9 more
doaj +1 more source
Haematologica, 2021 Von Willebrand factor (VWF) and factor VIII (FVIII) circulate in a noncovalent complex in blood and promote primary hemostasis and clotting, respectively.
Katarina D. Kovacevic +13 more
doaj +1 more source
Identification and characterisation of mutations associated with von Willebrand disease in a Turkish patient cohort [PDF]
, 2013 Several cohort studies have investigated the molecular basis of von Willebrand disease (VWD); however, these have mostly focused on European and North American populations.
Adel Abuzenadah +22 more
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European Journal of Haematology, EarlyView.ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman +10 more
wiley +1 more source
, 2017 Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
core +2 more sources