Acquired von Willebrand disease as a cause of recurrent mucocutaneous bleeding in primary thrombocythemia: Relationship with platelet count [PDF]
, 1994 We present a 4-year follow-up of a 42-year-old patient with primary thrombocythemia whose clinical course was complicated by two major mucocutaneous bleeding episodes.
Genderen, P.J.J. (Perry) van +3 more
core +1 more source
Platelet Dysfunction in Patients with Chronic Myeloid Leukemia: Does Imatinib Mesylate Improve It?
Turkish Journal of Hematology, 2016 INTRODUCTION: The aim of this study was to investigate the effects of imatinib mesylate on platelet aggregation and adenosine triphosphate (ATP) release in chronic myeloid leukemia patients. METHODS: Platelet aggregation and ATP release induced by 5.0 mM
Olga Meltem Akay +2 more
doaj +1 more source
Recent advances in the analysis of antibiotics by capillary electrophoresis [PDF]
, 2006 In this review, the main aspects related to the separation of different groups of antibiotics by CE as well as the different applications reported in the literature from the beginning 2003 till May 2005 will be provided to the readers.
García Ruiz, Carmen +1 more
core +2 more sources
Immunoinhibition of ristocetin-induced platelet aggregation. [PDF]
Journal of Clinical Investigation, 1977 Human platelets washed and fixed in paraformaldehyde aggregate in the presence of the antibiotic ristocetin and normal plasma. This aggregation response is abolished after digestion of the fixed platelets with chymotrypsin. Antisera to fixed washed platelets were produced in rabbits and absorbed with chymotrypsin-treated, fixed washed platelets ...
Babette B. Weksler +2 more
openaire +3 more sources
Biological properties of ristocetin-.PSI.-aglycone.
The Journal of Antibiotics, 1982 Ristocetin-ps-aglycone obtained by acid hydrolysis of ristocetin A, has a substantially greater antimicrobial activity against Gram-positive bacteria than the parent compound. None of the substances are active against Gram-negative bacteria, yeast or fungi.
F. Hyldig-Nielsen +2 more
openaire +4 more sources
Endothelial microparticles induce formation of platelet aggregates via a von Willebrand factor/ristocetin dependent pathway, rendering them resistant to dissociation [PDF]
Journal of Thrombosis and Haemostasis, 2005 W. Jy +7 more
semanticscholar +2 more sources
Identification and characterisation of mutations associated with von Willebrand disease in a Turkish patient cohort [PDF]
, 2013 Several cohort studies have investigated the molecular basis of von Willebrand disease (VWD); however, these have mostly focused on European and North American populations.
Adel Abuzenadah +22 more
core +1 more source
Haematologica, 2021 Von Willebrand factor (VWF) and factor VIII (FVIII) circulate in a noncovalent complex in blood and promote primary hemostasis and clotting, respectively.
Katarina D. Kovacevic +13 more
doaj +1 more source
Studies on the mechanism of ristocetin-induced platelet aggregation [PDF]
Blood, 1975 Adenine nucleotide metabolism and the release reaction were studied during ristocetin-induced platelet aggregation. Decreasing platelet ATP by incubation with metabolic poisons did not decrease ristocetin- induced aggregation. ADP and ATP were released from platelets during ristocetin-induced aggregation, and ATP was converted to hypoxanthine. However,
MH Gomez, HE Kattlove
openaire +4 more sources
Frontiers in Pharmacology, 2019 HD1 and HD22 are two of the most-studied aptamers binding to thrombin exosite I and exosite, respectively. To complete of their pharmacological profiles, the effects of HD1 and HD22 on thrombin-, ristocetin-, and collagen-induced human platelet ...
Katarzyna Derszniak +11 more
doaj +1 more source