Results 51 to 60 of about 9,310 (270)

Study on the Ristocetin-precipitated fibrinogen and Ristocetin induced platelet aggregation

Blood & Vessel, 1977
Howard arid Firkin have described that the ristocetin induced platelet aggregation (RIPA) is defective in von Willebrand's disease (vWd), but is normal in afibrinogenemia. They also noted that ristocetin causes precipitation of fibrinogen. A key factor of RIPA seems to be the factor lacking in vWd, not fibrinogen, since a plasma level of fibrinogen is ...
Humito KATO, Katsumi DEGUCHI, Seiichiro KAWAI, Makoto KUTO, Masaaki KONISHI, Masami KATO, Hisashi BEPPU, Katsura KUSUNOSE, Yuya IZUCHI, Sotoharu YAMADA   +9 more
openaire   +2 more sources

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

Autosomal dominant C1149R von Willebrand disease: phenotypic findings and their implications

Haematologica, 2009
Background Mutation C1149R in the von Willebrand factor (VWF) gene has been thought to cause autosomal dominant severe type 1 von Willebrand disease (VWD).Design and Methods Eight patients from three unrelated families with this mutation were included in
Almudena Pérez-Rodríguez, Aranzazu García-Rivero, Esther Lourés, Maria Fernanda López-Fernández, Angela Rodríguez-Trillo, Javier Batlle   +5 more
doaj   +1 more source

Influences of ABO blood group, age and gender on plasma coagulation factor VIII, fibrinogen, von Willebrand factor and ADAMTS13 levels in a Chinese population [PDF]

PeerJ, 2017
Background ABO blood group is a hereditary factor of plasma levels of coagulation factor VIII (FVIII) and von Willebrand factor (VWF). Age and gender have been shown to influence FVIII, VWF, fibrinogen (Fbg), and ADAMTS13 (A disintegrin and ...
Zongkui Wang, Miaomiao Dou, Xi Du, Li Ma, Pan Sun, Haijun Cao, Shengliang Ye, Peng Jiang, Fengjuan Liu, Fangzhao Lin, Rong Zhang, Changqing Li   +11 more
doaj   +2 more sources

Bernard‐Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Mohamed Lemine Salem, Ektelbenina Zein, Ghaber Sidi Mohamed   +2 more
wiley   +1 more source

Bernard-Soulier-like functional platelet defect in myelodysplastic syndrome and in acute myeloblastic leukemia associated with trilineage myelodysplasia

The Turkish Journal of Pediatrics, 1995
Platelet function was studied in a child with myelodysplastic syndrome (MDS: refractory anemia with an excess of blasts) and a child with acute myeloblastic leukemia (AML-M6) associated with trilineage myelodysplasia (TMDS).
G Hiçsönmez, F Gümrük, M Cetin, N Ozbek, M Tuncer, T Gürsel   +5 more
doaj  

A rare case of acquired von Willebrand syndrome type 2B: diagnosis, treatment, and underlying pathophysiology

Research and Practice in Thrombosis and Haemostasis
Background: Acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder that usually mimics type 1 or 2A von Willebrand disease (VWD). Key Clinical Question: Can AVWS mimic the phenotype of type 2B VWD?
Simon Jaouen, Fanny Mingant, Brigitte Pan-Petesch, Eric Lippert, Emmanuelle Jeanpierre, Hubert Galinat   +5 more
doaj   +1 more source

Outcomes and Healthcare Resource Utilisation in Adults With von Willebrand Disease Receiving On‐Demand Recombinant von Willebrand Factor in the United Kingdom

European Journal of Haematology, Volume 116, Issue 1, Page 66-74, January 2026.
ABSTRACT Objectives We describe treatment outcomes and healthcare resource utilisation (HCRU) in adults with von Willebrand disease (VWD) treated on demand with recombinant von Willebrand factor (rVWF) in the United Kingdom. Methods Retrospective chart review of adults (≥ 18 years) with congenital VWD receiving first‐time rVWF for the on‐demand ...
Mike Laffan, Heena Howitt, Cheryl Jones, Sarah Brighton, Rosa Willock, Anna Sanigorska, Oliver Heard   +6 more
wiley   +1 more source

INVESTIGATION OF RISTOCETIN-INDUCED PLATELET AGGREGATION, PARAMETERS OF VON WILLEBRAND FACTOR AND THE COAGULATION FACTOR VIII AT ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN

Acta Biomedica Scientifica, 2014
Ristocetin-induced platelet aggregation, von Willebrand factor and coagulation factor VIII of 170 children with essential arterial hypertension and 40 healthy children were investigated.
M. V. Gomellya
doaj  

Lymphoma‐associated acquired von Willebrand syndrome responsive to splenectomy: A case report

eJHaem, 2022
A previously healthy 33‐year‐old female presented with a large hematoma over her right knee after kneeling. She was found to have pancytopenia and massive splenomegaly.
Fatima Khadadah, Natasha Rupani, Jordan Scott, Martina Trinkaus, Jerome Teitel, Michelle Sholzberg   +5 more
doaj   +1 more source