Results 51 to 60 of about 32,676 (224)

Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients

Clinical and Applied Thrombosis/Hemostasis
Rivaroxaban was FDA-approved in 2019 for venous thromboembolism (VTE) prophylaxis in acutely ill hospitalized patients. Little to no published data is available to determine the level of correlation between rivaroxaban drug concentration and UFH/LMWH ...
Kaitlin Blotske PharmD, Toral Patel PharmD, BCPS, Toby Trujillo PharmD, FCCP, FAHA, BCPS, Matthew Marlar MLS (ASCP), Stuart Lind MD, Henry Kramer MD, Kathryn Hassell MD, Tyree H. Kiser PharmD, FCCM, FCCP, BCCCP, BCPS   +7 more
doaj   +1 more source

Rivaroxaban-loaded SLNs with treatment potential of deep vein thrombosis: in-vitro, in-vivo, and toxicity evaluation

, 2023
Rivaroxaban (RXB), a novel Xa inhibitor having groundbreaking therapeutic potential. However, this drug is associated with few limitations, including its pharmacokinetics related toxicities.
Sadia Sarwar (10712950), Aiman Saleem (16618607), Xuemei Luo (65327), Kalim Ullah (8456685), Muhammad Imran (282621), Alam Zeb (4010882), Uswa Shafique (16618610), Fakhar ud Din (12869555)   +7 more
core   +1 more source

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen, Nahawand Bahash, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Rivaroxaban Induced Hallucinations: A Case Report

, 2022
Hallucinations induced by rivaroxaban are not much described in literature. This case report describes the occurrence of a specific adverse event during rivaroxaban use in an elderly male who developed hallucinations few months after starting rivaroxaban.
Matthew Ferguson, Anshika Balwan
core   +1 more source

The Cancer Immunotherapy Thromboembolism Assessment: A Novel Score for Predicting Thromboembolic Events in Melanoma Patients Treated With Immune Checkpoint Inhibition

International Journal of Cancer, EarlyView.
Although immune checkpoint inhibitors (ICI) have transformed metastatic melanoma treatment, thromboembolic events (TEEs) remain a serious complication. Moreover, existing risk assessment models were developed prior to ICI use and lack clinical validation.
Tim Zell, Julian Kött, Noah Zimmermann, Greta Ancker, Alexander T. Bauer, Daniel J. Smit, Glenn Geidel, Julian C. Gerwers, Thomas Renné, Sebastian A. Wohlfeil, Jochen Utikal, Stefan W. Schneider, Christoffer Gebhardt   +12 more
wiley   +1 more source

Cost-effectiveness and budget impact analysis of rivaroxaban with or without aspirin compared to aspirin alone in patients with coronary and peripheral artery diseases in Iran

BMC Health Services Research
Background Low-dose aspirin and rivaroxaban are the cornerstone treatment for cardiovascular prevention in patients with peripheral artery disease (PAD) and/or stable coronary artery disease (SCAD).
Zahra Goudarzi, Zhila Najafpour, Ahmad Gholami, Khosro Keshavarz, Mohammad Mahdi Mojahedian, Mohammad Mehdi Babayi   +5 more
doaj   +1 more source

Effects of thromboprophylactic doses of apixaban and rivaroxaban on coagulation and thrombin generation in association with total hip replacement [PDF]

, 2017
Factor Xa inhibitors (FXaI) apixaban and rivaroxaban are used for thromboprophylaxis after major elective orthopaedic surgery. Because few patient sample studies exist, we postoperatively assessed patients undergoing unilateral total hip arthroplasty ...
Lassila, Riitta, Jarkko Leskinen, Lotta Joutsi-Korhonen, Joutsi-Korhonen, Lotta, Lauri Virtanen, Helin, Tuukka A., Riitta Lassila, Mikko Manninen, Leppilahti, Juhana, Tuukka A. Helin, Juhana Leppilahti, Virtanen, Lauri, Manninen, Mikko, Leskinen , Jarkko   +13 more
core   +1 more source

Measurement of Active Thrombin Bound to Circulating D‐Dimers as a Sensitive Biomarker for Prothrombotic Conditions

Journal of Clinical Laboratory Analysis, EarlyView.
Scheme of preparation of D‐dimers and evaluation of D‐dimer‐bound thrombin activity. Thrombin bound to fibrin participates in ongoing fibrinogen transformation and its inhibition is impeded. Our detection system may aid in identifying patients at risk of recurrent thrombotic events or complications, regardless of the origin of the acute health problem.
Jana Stikarova, Leona Chrastinova, Kristyna Svobodova, Marek Havlicek, Jan Louzil, Eliska Ceznerova, Alzbeta Hlavackova, Ondrej Pastva, Pavla Pecherkova, Ingrid Hrachovinova, Ondrej Kucerka, Roman Kotlin, Petr Soukup, Peter Salaj, Martin Maly, Jiri Suttnar   +15 more
wiley   +1 more source

Incidence, contributing factors, and predictors of diagnostic errors in medical inpatients: A retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx, Elena Hofmann, Martin Perrig, Gurpreet Dhaliwal, Wolf Hautz, Jörg P. Isenegger, Ernst Lipp, Drahomir Aujesky, Manuel R. Blum, Tobias Tritschler   +9 more
wiley   +1 more source

Fatigue after initiating rivaroxaban for venous thromboembolism [PDF]

, 2020
Background Rivaroxaban was the first new oral anticoagulant approved for treatment of venous thromboembolism (VTE). Clinical trials have shown that rivaroxaban is noninferior to conventional anticoagulation for VTE in efficacy and safety.
Jørgensen, Camilla Tøvik, Ghanima, Waleed Khalid, Borgenvik, Thore Langfeldt, Utne, Kristin Kornelia, Jelsness-Jørgensen, Lars-Petter, Holst, René, Aadalen, Mirjam, Karlsvik, Tina Margrethe, Førsund, Eli   +8 more
core   +1 more source