Results 31 to 40 of about 58,868 (161)

Recurrent pancreatic cancer treated with N-803 and PD-L1 t-haNK followed by an EGFR-targeted nanocell drug conjugate

The Oncologist
Multimodal temporal therapy orchestrated to leverage immunotherapy, tumor-targeted chemotherapy, and natural killer (NK) cell therapy may provide an opportunity to induce immunogenic cell death for tumor response and increased survival in patients with ...
Katayoun Moini, T. Seery, C. Nangia, J. MacDiarmid, H. Brahmbhatt, Patricia Spilman, Lennie Sender, P. Soon-Shiong   +7 more
semanticscholar   +1 more source

Bidirectional Relationship Between Atopic Dermatitis and Psychiatric Comorbidities in Individuals of European Ancestry: A Mendelian Randomization Study

Acta Dermato-Venereologica
Atopic dermatitis is a chronic inflammatory skin disorder that significantly impacts quality of life and is often associated with psychiatric comorbidities.
Zhe Wu, Chenglong Wu, Xuanyi Chen, Qiufang Qian, Zhirong Yao   +4 more
doaj   +1 more source

Theoretical calculations of molecular descriptors for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against gastric cancer cell line (MGC-803): DFT, QSAR and docking approaches

Heliyon, 2020
s This work used quantum chemical method via DFT to calculate molecular descriptors for the development of QSAR model to predict bioactivity (IC50- 50% inhibition concentration) of the selected 1, 2, 3-triazole-pyrimidine derivatives against receptor ...
R. O. Oyewole, A. Oyebamiji, B. Semire
semanticscholar   +1 more source

Application of Radiofrequency Ablation for the Treatment of Cutaneous Hemangioma and Vascular Malformation in a Cockscomb Model

Dermatology Research and Practice
Conclusion: RFA significantly reduced the capillary number and promoted tissue fibrosis. Compared with bleomycin, RFA showed a better effect and with no obvious side effects in treating a cockscomb model of cutaneous hemangioma and vascular malformation.
Hong-long Chen, Dong-mei Li, Xi-sheng Lin, Xiao Zhang, Tao Chen, Wei Chen, Yue-ming Gao   +6 more
doaj   +1 more source

Rates of Infections, Malignancies, Cardiovascular Outcomes, and Death in Individuals with Hospital-treated Alopecia Areata: A Registry-based Cohort Study in Denmark

Acta Dermato-Venereologica
The emergence of new systemic treatments for alopecia areata underscores the importance of estimating rates of potential treatment safety events among individuals with alopecia areata.
Sissel Brandt Toft Sørensen, Prethibha George, Oladayo Jagun, Robert Wolk, Lynne Napatalung, Samuel H. Zwillich, Lars Iversen, Vera Ehrenstein   +7 more
doaj   +1 more source

Stevens-Johnson syndrome and toxic epidermal necrolysis in Saudi Arabia: a retrospective cross-sectional multicenter study

Dermatology Reports
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a spectrum of life-threatening mucocutaneous conditions. Despite having a lower incidence rate than other dermatological conditions, SJS/TEN has a high mortality rate.
Rayan Alkhodair, Yazeed Alowairdhi, Abdulrahman Alfawzan, Ali Alghamdi   +3 more
doaj   +1 more source

Alopecia Areata: Impact on Patients’ Quality of Life and Disease Perception: A Survey-Based Study

Acta Dermato-Venereologica
Alopecia areata significantly impacts patients’ emotional and psychosocial well-being. This survey investigated patients’ perspectives on disease severity and its impact on quality of life.
Christian Vestergaard, Daniel de la Rosa Carrillo, Randeep Mandla, Anne Grete Frøstrup, Susanne T. Gren, Petri Vänni, Anna-Kaisa Asikainen, Kristian Kofoed, Cato Mørk   +8 more
doaj   +1 more source

Patterns of Complementary and Alternative Medicine Use among Psoriasis Patients in a Tertiary Care Hospital in South India – A Cross-sectional Study

Clinical Dermatology Review
Background: Complementary and alternative medicine (CAM) refers to medical practices that are not part of conventional medicine. Reports in literature suggest the prevalence of CAM use ranges from 37% to 87%.
Adithya Chandran, Saritha Mohanan, B Maharani   +2 more
doaj   +1 more source

DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway

Oxidative Medicine and Cellular Longevity, 2020
Epithelial-mesenchymal transition (EMT) is a cellular process in which epithelial cells are partially transformed into stromal cells, which endows the polarized epithelium cells more invasive feature and contributes cancer metastasis and drug resistance.
Jiankang Feng, Cuiping Li, Ruifang Xu, Yongli Li, Q. Hou, Rui Feng, Senye Wang, Lei Zhang, Changzheng Li   +8 more
semanticscholar   +1 more source

Case–Control Study of Inflammatory Mediators in Psoriasis and its Correlation with the Psoriasis Area and Severity Index

Clinical Dermatology Review
Background: Acute-phase reactants (APRs) in psoriasis are especially released under the influence from the liver of interleukin (IL)-6 that include serum amyloid A, ceruloplasmin, ferritin, complements, haptoglobin, fibrinogen, C-reactive protein, and ...
Jeevith Chandrashekara Reddy, Y Hari Kishan Kumar   +1 more
doaj   +1 more source