Results 51 to 60 of about 191,275 (167)

CGRP Is Critical for Hot Flushes in Ovariectomized Mice

open access: yesFrontiers in Pharmacology, 2019
Hot flushes are common and troublesome symptoms of menopause. The neuropeptide calcitonin gene-related peptide (CGRP) is increased in plasma during hot flushes but it has not been clear if CGRP is causally involved in the mechanism underpinning the ...
Daniel B. Wilhelms   +12 more
doaj   +1 more source

Enhanced Artificial Rabbits Algorithm Integrating Equilibrium Pool to Support PV Power Estimation via Module Parameter Identification

open access: yesInternational Journal of Energy Research, Volume 2024, Issue 1, 2024.
This paper proposes a novel innovative version of enhanced artificial rabbit optimization (EARO) algorithm integrating an equilibrium pool (EP) that consists of the best solutions. Furthermore, the detour foraging and hiding mechanisms are modified to amplify the search capability.
Idris H. Smaili   +6 more
wiley   +1 more source

Gender Differences in Outpatient Pediatric Drug Utilization: A Cohort Study From Southern Italy

open access: yesFrontiers in Pharmacology, 2019
Objective: The aim of this retrospective population-based cohort study is to in-depth investigate gender-specific drug utilization pattern in pediatric outpatient population.Methods: By using a large administrative database of the Local Health Unit of ...
Carmen Ferrajolo   +12 more
doaj   +1 more source

Application of the Nested Enzyme‐Within‐Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2020
The gut wall consists of many biological elements, including enterocytes. Rapid turnover, a prominent feature of the enterocytes, has generally been ignored in the development of enterocyte‐targeting drugs, although it has a comparable rate to other ...
Hiroyuki Takita   +3 more
doaj   +1 more source

Distance reporting in digital pathology: A study on 950 cases

open access: yesJournal of Pathology Informatics, 2015
Background: Increased workload, case complexity, financial constraints, and staffing shortages justify wider implementations of digital pathology. One of its main advantages is distance reporting. Aim: A feasibility study was conducted at our institution
A. Vodovnik
semanticscholar   +1 more source

Semiempirical Quantum Chemistry Model for the Lanthanides: RM1 (Recife Model 1) Parameters for Dysprosium, Holmium and Erbium

open access: yesPLoS ONE, 2014
Complexes of dysprosium, holmium, and erbium find many applications as single-molecule magnets, as contrast agents for magnetic resonance imaging, as anti-cancer agents, in optical telecommunications, etc.
Manoel A. M. Filho   +4 more
semanticscholar   +1 more source

Pharmacological intervention of HIV-1 maturation

open access: yesActa Pharmaceutica Sinica B, 2015
Despite significant advances in antiretroviral therapy, increasing drug resistance and toxicities observed among many of the current approved human immunodeficiency virus (HIV) drugs indicate a need for discovery and development of potent and safe ...
Dan Wang, Wuxun Lu, Feng Li
doaj   +1 more source

Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

open access: yesFrontiers in Pharmacology, 2020
The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons. Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive-compulsive disorder.
Angélica del Pilar Escobar   +4 more
doaj   +1 more source

Effects of microwaves (950 MHZ mobile phone) on morphometric and apoptotic changes of rabbit epididymis

open access: yesAndrologia, 2015
The effect of mobile phone radiation on human reproduction system is still a matter of debate. In this study, 18 male rabbits were randomly divided into two experimental groups and one control group. Experimental groups received simulated microwaves with
E. A. Oskouyi   +4 more
semanticscholar   +1 more source

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