Results 71 to 80 of about 201,194 (169)

The dual roles of serotonin in antitumor immunity

Pharmacological Research
Research has shown that a significant portion of cancer patients experience depressive symptoms, often accompanied by neuroendocrine hormone imbalances.
Yingru Zhang, Yan Wang
doaj   +1 more source

Peculiar Phosphonate Modifications of Velvet Worm Slime Revealed by Advanced Nuclear Magnetic Resonance and Mass Spectrometry. [PDF]

J Am Chem Soc, 2023
Poulhazan A, Baer A, Daliaho G, Mentink-Vigier F, Arnold AA, Browne DC, Hering L, Archer-Hartmann S, Pepi LE, Azadi P, Schmidt S, Mayer G, Marcotte I, Harrington MJ.   +13 more
europepmc   +1 more source

Novel strategies for targeting neutrophil against myocardial infarction

Pharmacological Research
Inflammation is a crucial factor in cardiac remodeling after acute myocardial infarction (MI). Neutrophils, as the first wave of leukocytes to infiltrate the injured myocardium, exacerbate inflammation and cardiac injury.
Kai Jiang, John Hwa, Yaozu Xiang
doaj   +1 more source

Electroacupuncture at HT5 + GB20 promotes brain remodeling and significantly improves swallowing function in patients with stroke. [PDF]

Front Neurosci, 2023
Fu X, Li H, Yang W, Li X, Lu L, Guo H, Guo K, Huang Z.   +7 more
europepmc   +1 more source

Understanding patient demand for and use of antibiotics for upper respiratory tract infection: A qualitative application of the Necessity-Concerns Framework in Saudi Arabia

Frontiers in Pharmacology
BackgroundReducing antimicrobial resistance (AMR) is a priority for public health. Inappropriate patient demand is an important driver of unnecessary antibiotic use.
Nouf Almeshal, Nouf Almeshal, Holly Foot, Amy Louise Clarke, Amy Hai Yan Chan, Rob Horne   +5 more
doaj   +1 more source

Ferroptosis resistance in cancer cells: nanoparticles for combination therapy as a solution

Frontiers in Pharmacology
Ferroptosis is a form of regulated cell death (RCD) characterized by iron-dependent lipid peroxidation. Ferroptosis is currently proposed as one of the most promising means of combating tumor resistance.
Kodzo Prosper Adzavon, Weijian Zhao, Xuesong He, Wang Sheng   +3 more
doaj   +1 more source

Punicalagin Restricts Growth, Promotes Apoptosis, and Reduces Invasion in Human Gastric Cancer Cells

Dose-Response
This research investigated the anticancer properties of punicalagin, a prominent bioactive polyphenol extracted from Punica granatum L, in human gastric cancer cell lines. Normal and gastric cancer cells were exposed to different doses of punicalagin for
Ding-Ping Sun, Yih-Huei Uen, Nai-Wen Kang, Chun-Chao Chang, Yu-Feng Tian, Chia-Lang Fang, Kai-Yuan Lin   +6 more
doaj   +1 more source

Electroencephalographic insights into the pathophysiological mechanisms of emergence delirium in children and corresponding clinical treatment strategies

Frontiers in Pharmacology
Emergence delirium is a common postoperative complication in patients undergoing general anesthesia, especially in children. In severe cases, it can cause unnecessary self-harm, affect postoperative recovery, lead to parental dissatisfaction, and ...
Xin Gao, Zhichao Li, Jun Chai, Si Li, Xuanyuan Pan, Jie Liu, Linxing Li, Shangyuan Qin, Yihan Kang, Youzhuang Zhu   +9 more
doaj   +1 more source

Synergistic interaction network between the snR30 RNP, Utp23, and ribosomal RNA during ribosome synthesis. [PDF]

RNA Biol, 2022
Vos TJ, Kothe U.
europepmc   +1 more source

Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2

Antioxidants
Glutathione (GSH), a robust endogenous antioxidant, actively participates in the modulation of the redox status of cysteine residues in proteins. Previous studies have indicated that GSH can prevent β-cell failure and prediabetes caused by chronic ...
Xiufang Chen, Qian Zhou, Huamin Chen, Juan Bai, Ruike An, Keyi Zhang, Xinyue Zhang, Hui An, Jitai Zhang, Yongyu Wang, Ming Li   +10 more
doaj   +1 more source