Results 41 to 50 of about 13,275 (183)

Correlations among the plasma concentrations of first-line anti-tuberculosis drugs and the physiological parameters influencing concentrations

Frontiers in Pharmacology, 2023
Background: The plasma concentrations of the four most commonly used first-line anti-tuberculosis (TB) drugs, isoniazid (INH), rifampicin (RMP), ethambutol (EMB), and pyrazinamide (PZA), are often not within the therapeutic range.
Lin Cheng, Ming Luo, Yan Guo, Yunfan Fan, Pengsen Wang, Gang Zhou, Shiwei Qin, Bangbi Weng, Peibo Li, Zhirui Liu, Songtao Liu   +10 more
doaj   +1 more source

Are seizure forecasts and cycles better than chance? What chance?

Epilepsia, EarlyView.
Abstract Objective There is a growing synergy between the lines of research on cycles in epilepsy and seizure forecasting. It has been conjectured, for instance, that incorporating information about significant seizure cycles into forecasting algorithms can lead to a better‐than‐chance forecasting performance.
Ralph G. Andrzejak, Martin Brešar, Mark P. Richardson, Pedro F. Viana, Richard Rosch   +4 more
wiley   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains isolated in Brazil and France

Memorias do Instituto Oswaldo Cruz, 2001
We evaluated the mutations in a 193bp of the rpoB gene by automated sequencing of rifampicin (RMP)-resistant and susceptible Mycobacterium tuberculosis strains isolated from Brazil (25 strains) and France (37 strains). In RMP-resistant strains, mutations
S Spindola de Miranda, AL Kritski, I Filliol, C Mabilat, G Panteix, E Drouet   +5 more
doaj   +1 more source

Out of the lab, into real life: Evaluating at‐home EEG self‐monitoring

Epilepsia Open, EarlyView.
Abstract Seizure forecasting models require long‐term, high‐quality data collected in real‐life settings using noninvasive or minimally invasive devices, yet, the lack of such systems remains a major barrier to their clinical translation. Here, we aimed to evaluate the signal quality of self‐applied at‐home EEG monitoring using a wearable system in ...
Louis Cousyn, Andrea Biondi, Joel S. Winston, Matthew McWilliam, Pedro F. Viana, Martijn Schreuder, Petroula Laiou, Mark P. Richardson   +7 more
wiley   +1 more source

SRF - RMP - Course.pptx

, 2020
Risk
openaire   +1 more source

Trajectories of child emotional and behavioural difficulties before and during the COVID‐19 pandemic in a longitudinal UK cohort

JCPP Advances, EarlyView.
Abstract Background There are substantial age‐related changes in emotional and behavioural problems over childhood. In order to establish the impact of the Covid‐19 pandemic on child emotional and behavioural problems, longitudinal designs which take into account age‐related trends are needed.
Nicky Wright, Daphne Kounali, Elise Paul, Alex S. F. Kwong, Daniel Major‐Smith, Ilaria Costantini, Deborah A. Lawlor, Kapil Sayal, Helen Bould, Nicholas J. Timpson, Kate Northstone, Melanie Lewcock, Kate Tilling, Rebecca M. Pearson   +13 more
wiley   +1 more source

From Evidence to Practice: Implementation and Evaluation of the Discontinuation of Patient Contact Shielding in Paediatric Radiography

Journal of Medical Radiation Sciences, EarlyView.
This implementation science study evaluated the removal of patient contact shielding in paediatric radiography at a quaternary Australian hospital. Guided by the COM‐B model and Theoretical Domains Framework, the policy change was implemented with minimal disruption. Fewer than 0.5% of families raised any concerns, demonstrating that even long‐standing
Elaine Ryan, Kerrie Norynberg, Patricia Connor, Deborah Sinclair, Tristan Reddan   +4 more
wiley   +1 more source

Gastrointestinal manifestations following chimeric antigen receptor T‐cell (CAR‐T) 19 therapy in pediatric patients with CD19+ acute lymphoblastic leukemia

JPGN Reports, EarlyView.
Abstract Pediatric patients with CD19+ acute lymphoblastic leukemia (ALL) undergoing chimeric antigen receptor T‐cell (CAR‐T) therapy frequently experience gastrointestinal (GI) complications. A retrospective study analyzed 13 patients (median age: 8 years) treated between January 2020 and January 2024.
Judith Raya Muñoz, Melissa Panesso Romero, Saray Mesonero Cavia, Marta Freixas Bermejo, Vanessa Cabello Ruiz, Marina Álvarez Beltran, Maria Cristina Díaz de Heredia Rubio, Susana Elena Redecillas Ferreiro, Oscar Segarra Canton   +8 more
wiley   +1 more source