Results 51 to 60 of about 13,275 (183)

Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3 [PDF]

Journal of Virology, 1992
At least three genes from C57BL/6 mice that mediate dominant resistance to lethal mousepox were isolated and transferred onto a susceptible DBA/2 background. Three [(C57BL/6 x DBA/2)F1 x DBA/2] male mice that survived infection were selected as founders on the basis of different complements of marker loci for two resistance genes, Rmp-2r (Hc1) and Rmp ...
D G, Brownstein, P N, Bhatt, L, Gras, T, Budris   +3 more
openaire   +2 more sources

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Substrate‐Tight Graphene Transmembrane‐nanofluidic Devices

Small, EarlyView.
This study demonstrates that the covalent coupling of a pyrene layer to a silicon nitride substrate using silane and peptide chemistry increases the adhesion of graphene to the substrate and prevents the delamination of graphene. 76.2% of the devices with free‐standing graphene are successful devices for ion transport measurement in 0.1 M HCl ...
Xiaofang Kang, Buhang Chen, Erik P. van Geest, Wangyang Fu, Jianwei Gao, Luzhao Sun, Zhongfan Liu, Grégory F. Schneider   +7 more
wiley   +1 more source

Convergent Interval Confirmation for Three‐Step Discrete Specific Zeroing Neural Dynamics Illustrated With Repetitive Motion Planning of Redundant Manipulators

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Repetitive motion planning (RMP) for redundant manipulators with high convergent precision becomes an intense research topic due to its more degrees of freedom. In this paper, a specific zeroing neural dynamics (SZND) model for the RMP is first set up via zeroing neurodynamics.
Ying Kong, Shaoyuan Sun, Yunliang Jiang, Lin Wei   +3 more
wiley   +1 more source

Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Immersive virtual reality (VR) technology offers a non‐invasive, non‐pharmacological approach to reduce pain perception in patients undergoing diagnostic or interventional procedures. Objective To systematically evaluate the efficacy of immersive VR technology in reducing pain perception during obstetric and gynaecological ...
Jhia Jiat Teh, Filipa Campos, Adam Koczoski, Trisha Valencia, Michael P. Rimmer, Bassel H. Al Wattar   +5 more
wiley   +1 more source

PSHead: 3D Head Reconstruction from a Single Image with Diffusion Prior and Self‐Enhancement

Computer Graphics Forum, EarlyView.
We introduce PSHead, a coarse‐to‐fine framework guided by both object and face priors, to produce a Gaussian‐based 3D avatar for a single frontal‐view reference image. In the coarse stage, we create an initial 3D representation by applying diffusion models trained for general object generation, using Score Distillation Sampling losses over novel views.
Jing Yang, Tianhan Wu, Kyle Fogarty, Fangcheng Zhong, Cengiz Oztireli   +4 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Practitioner Review: Clinical insights from attachment theory and research for professionals working with young children and their families

Journal of Child Psychology and Psychiatry, EarlyView.
Attachment theory, with its core concepts, perspectives, and insights developed over the past five decades, is influential for professionals working with young children. However, practitioners face challenges translating attachment theory and research into practical applications.
Jessica E. Opie, Everett Waters, Robbie Duschinsky, Mårten Hammarlund, Sheri Madigan, Sarah Foster, Tommie Forslund, Ross Thompson, Howard Steele, Miriam Steele, Glenn I. Roisman, Ashley M. Groh, Peter Fonagy, Or Dagan, Alessandro Talia, Larissa Rossen, L. Alan Sroufe, Ed Tronick, R. M. Pasco Fearon, Pehr Granqvist, Abraham Sagi‐Schwartz, Alicia Lieberman, Elizabeth Carlson, Peter Zimmermann, Mary Dozier, Ashley Wazana, Jay Belsky, Phillip R. Shaver, Dante Cicchetti, Guy Bosmans, Carlo Schuengel, Karin Grossmann, Chantal Cyr, Karine Dubois‐Comtois, Marije Verhage, Anne Tharner, Mirjam Oosterman, Brian Allen, Judith A. Crowell, Pascal Vrtička, Matthew Woolgar, K. Lee Raby, Megan Galbally, Jeremy Holmes, Robert S. Marvin, Marinus H. van IJzendoorn, Marian J. Bakermans‐Kranenburg   +46 more
wiley   +1 more source

Sparse Signal Recovery via Rescaled Matching Pursuit

Axioms
We propose the Rescaled Matching Pursuit (RMP) algorithm to recover sparse signals in high-dimensional Euclidean spaces. The RMP algorithm has less computational complexity than other greedy-type algorithms, such as Orthogonal Matching Pursuit (OMP).
Wan Li, Peixin Ye
doaj   +1 more source

Beyond high‐throughput: leveraging plant phenotyping to improve understanding and prediction of plant growth through process‐based models

New Phytologist, EarlyView.
Summary The last decade has marked a period of rapid innovation in high‐throughput phenotyping (HTP) of plants. This includes the establishment of robotic phenotyping infrastructure, development of new sensors, and improvements in computation for downstream analysis.
To‐Chia Ting, D. Scott Mackay, Jinha Jung, Matthew P. Reynolds, Yang Yang, Diane R. Wang   +5 more
wiley   +1 more source