Results 231 to 240 of about 959,158 (292)

Antisense Oligonucleotide-Mediated <i>XIST</i> Knockdown Modulates Endogenous Pluripotency-Associated Transcription Factor Expression in Porcine Female Somatic Cells. [PDF]

Animals (Basel)
Chen X, Chu X, Huang J, Zhang L, Lu F, Yang N, Dai L, Xu R.   +7 more
europepmc   +1 more source

Ginsenoside Rh1 Attenuates Alzheimer's Disease‐Like Deficits by Modulating Oxidative Stress and Mitochondrial Dysfunction via SIRT1‐Related Signaling

Phytotherapy Research, EarlyView.
Rh1 attenuates oxidative stress and mitochondrial dysfunction through SIRT1‐related signaling. ABSTRACT Alzheimer's disease (AD) remains a progressive neurodegenerative disorder with limited therapeutic options. Ginsenoside Rh1 has been reported to possess neuroprotective properties, yet its specific role and underlying mechanisms in AD are not fully ...
Shi‐Lu Li, Tao Lin, Wan‐chen Zou, Ya‐jun Wang, Jing‐tian Zhang, Zi Wang, Hong‐yuan Li, Long Chen, Li‐chun Zhao, Shen Ren, Wei Li   +10 more
wiley   +1 more source

Decoding MAPT Exon 10 Mis-Splicing in FTDP-17: From Pathogenic Mechanisms and Experimental Models to Molecular Therapies. [PDF]

Genes (Basel)
Covello G.
europepmc   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

Squash enables Spindle-E-dependent heterotypic piRNA amplification in the <i>Drosophila</i> ovary. [PDF]

iScience
Xu X, Iki T, Kawaguchi S, Kai T.
europepmc   +1 more source

RNA duplex formation and competing endogenous RNA, proposed as mechanisms in regulating expression of natural antisense transcripts- from hypotheses to potential therapeutic applications. [PDF]

Front Mol Biosci
Nakatake R, Okuyama T, Kimura T, Nishizawa M.   +3 more
europepmc   +1 more source

The lncRNA PHAROH augments MYC mRNA levels in insulin-producing cells by counteracting TIA1-induced MYC silencing. [PDF]

Sci Rep
Zhao T, Welsh N.
europepmc   +1 more source

AI-Guided Long Non-Coding RNA Target Discovery for Precision Medicine: Integrating GWAS, Multi-Omics, Experimental Validation, and RNA Therapeutics. [PDF]

Biomedicines
Ang MY, Chen L, Song L, Lipovich L, Choo SW.   +4 more
europepmc   +1 more source

Statement of Retraction: Involvement of long non-coding RNA ZNF503 antisense RNA 1 in diabetic retinopathy and its possible underlying mechanism. [PDF]

Bioengineered
europepmc   +1 more source

Recognition and silencing of a new transposable element. [PDF]

Nat Commun
Salvi L, Yan Y, Halic M.
europepmc   +1 more source