Results 11 to 20 of about 2,869,940 (329)
RNA Thermometers in Bacterial Pathogens [PDF]
Microbiology Spectrum, 2018 Temperature variation is one of the multiple parameters a microbial pathogen encounters when it invades a warm-blooded host. To survive and thrive at host body temperature, human pathogens have developed various strategies to sense and respond to their ...
E. Loh +4 more
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The bacterial enhancer-dependent RNA polymerase [PDF]
Biochemical Journal, 2016 Transcription initiation is highly regulated in bacterial cells, allowing adaptive gene regulation in response to environment cues. One class of promoter specificity factor called sigma54 enables such adaptive gene expression through its ability to lock ...
Nan Zhang +4 more
semanticscholar +6 more sources
Regulating Bacterial Virulence with RNA. [PDF]
Annual Review of Microbiology, 2017 Noncoding RNAs (ncRNAs) regulating virulence have been identified in most pathogens. This review discusses RNA-mediated mechanisms exploited by bacterial pathogens to successfully infect and colonize their hosts. It discusses the most representative RNA-mediated regulatory mechanisms employed by two intracellular [Listeria monocytogenes and Salmonella ...
J. Quereda, P. Cossart
semanticscholar +5 more sources
Bacterial RNA Biology on a Genome Scale. [PDF]
Molecular Cell, 2018 Bacteria are an exceedingly diverse group of organisms whose molecular exploration is experiencing a renaissance. While the classical view of bacterial gene expression was relatively simple, the emerging view is more complex, encompassing extensive post-transcriptional control involving riboswitches, RNA thermometers, and regulatory small RNAs (sRNAs ...
Jens Hör, S. Gorski, J. Vogel
semanticscholar +4 more sources
FEMS Microbiology Reviews, 2015 Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
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Processing of bacterial RNA [PDF]
FEBS Letters, 1981 Processing of RNA is a feature of RNA metabolism which contributes to the determination of the fmal population of active RNA molecules in the cell. Pro- cessing is the sum of events which converts a primary RNA transcript into a functional molecule. RNA processing in bacteria consists mainly of two parts, modification of nucleotides and cutting and ...
David Apirion, Peter Gegenheimer
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RNAs: regulators of bacterial virulence [PDF]
Nature Reviews Microbiology, 2010 RNA-based pathways that regulate protein expression are much more widespread than previously thought. Regulatory RNAs, including 5' and 3' untranslated regions next to the coding sequence, cis-acting antisense RNAs and trans-acting small non-coding RNAs, are effective regulatory molecules that can influence protein expression and function in response ...
Jonas Gripenland +5 more
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Bacterial Small RNA Regulators [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2005 Small regulatory RNAs can modify the activity of proteins and the stability and translation of mRNAs. They have now been found in a wide range of organisms, and can play previously unsuspected critical regulatory roles. The bacterial small RNAs include two major classes.
Majdalani, Nadim +2 more
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Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model
Heliyon, 2023 The SARS-CoV2 Omicron variants have acquired new Spike mutations leading to escape from the most of the currently available monoclonal antibody treatments reducing the options for patients suffering from severe Covid-19.
Cécile Hérate +13 more
doaj +1 more source
Regulatory RNA in Bacterial Pathogens [PDF]
Cell Host & Microbe, 2010 Bacteria constitute a large and diverse class of infectious agents, causing devastating diseases in humans, animals, and plants. Our understanding of gene expression control, which forms the basis for successful prevention and treatment strategies, has until recently neglected the many roles that regulatory RNAs might have in bacteria. In recent years,
Jörg Vogel, Kai Papenfort
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