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Metatranscriptomic profiling reveals pathogen and host response signatures of pediatric acute sinusitis and upper respiratory infection [PDF]
Genome MedicineBackground Acute sinusitis (AS) is a frequent cause of antibiotic prescriptions in children. Distinguishing bacterial AS from common viral upper respiratory infections (URIs) is crucial to prevent unnecessary antibiotic use but is challenging with ...
Andrew C. Doxey +12 more
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Quantitative bacterial transcriptomics with RNA-seq. [PDF]
Current Opinion in Microbiology, 2015 RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters, terminators, operons, among ...
J. Creecy, T. Conway
semanticscholar +4 more sources
Frontiers in Veterinary Science, 2023 Bacteria of the genus Salmonella pose a major risk to livestock, the food economy, and public health. Salmonella infections are one of the leading causes of food poisoning.
Christine Thomas +4 more
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Bacterial Response to Oxidative Stress and RNA Oxidation
Frontiers in Genetics, 2022 Bacteria have to cope with oxidative stress caused by distinct Reactive Oxygen Species (ROS), derived not only from normal aerobic metabolism but also from oxidants present in their environments.
André F. Seixas +5 more
semanticscholar +1 more source
FEMS Microbiology Reviews, 2015 Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
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Processing of bacterial RNA [PDF]
FEBS Letters, 1981 Processing of RNA is a feature of RNA metabolism which contributes to the determination of the fmal population of active RNA molecules in the cell. Pro- cessing is the sum of events which converts a primary RNA transcript into a functional molecule. RNA processing in bacteria consists mainly of two parts, modification of nucleotides and cutting and ...
David Apirion, Peter Gegenheimer
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BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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Parasites & Vectors, 2022 Background Lyme borreliosis is the most prevalent vector-borne disease in Europe, and numbers might increase due to climate change. However, borreliosis is not notifiable in North Rhine-Westphalia (NRW), Germany.
Annabell Coors +6 more
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Microorganisms, 2022 Lyme borreliosis is the leading tick-related illness in Europe, caused by Borrelia Burgdorferi s.l. Lower Saxony, Germany, including its capital, Hanover, has a higher proportion of infected ticks than central European countries, justifying a research ...
Max J. Hassenstein +7 more
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RNAs: regulators of bacterial virulence [PDF]
Nature Reviews Microbiology, 2010 RNA-based pathways that regulate protein expression are much more widespread than previously thought. Regulatory RNAs, including 5' and 3' untranslated regions next to the coding sequence, cis-acting antisense RNAs and trans-acting small non-coding RNAs, are effective regulatory molecules that can influence protein expression and function in response ...
Jonas Gripenland +5 more
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