Results 11 to 20 of about 477,009 (248)

RNA Thermometers in Bacterial Pathogens [PDF]

open access: yesMicrobiology Spectrum, 2018
ABSTRACT Temperature variation is one of the multiple parameters a microbial pathogen encounters when it invades a warm-blooded host. To survive and thrive at host body temperature, human pathogens have developed various strategies to sense and respond to their ambient temperature.
Francesco Righetti   +5 more
openaire   +4 more sources

Bacterial Small RNA Regulators [PDF]

open access: yesCritical Reviews in Biochemistry and Molecular Biology, 2005
Small regulatory RNAs can modify the activity of proteins and the stability and translation of mRNAs. They have now been found in a wide range of organisms, and can play previously unsuspected critical regulatory roles. The bacterial small RNAs include two major classes.
Majdalani, Nadim   +2 more
openaire   +2 more sources

Regulatory RNA in Bacterial Pathogens [PDF]

open access: yesCell Host & Microbe, 2010
Bacteria constitute a large and diverse class of infectious agents, causing devastating diseases in humans, animals, and plants. Our understanding of gene expression control, which forms the basis for successful prevention and treatment strategies, has until recently neglected the many roles that regulatory RNAs might have in bacteria. In recent years,
Jörg Vogel, Kai Papenfort
openaire   +3 more sources

Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model

open access: yesHeliyon, 2023
The SARS-CoV2 Omicron variants have acquired new Spike mutations leading to escape from the most of the currently available monoclonal antibody treatments reducing the options for patients suffering from severe Covid-19.
Cécile Hérate   +13 more
doaj   +1 more source

RETRACTED: Bacterial persistence by RNA endonucleases [PDF]

open access: yesProceedings of the National Academy of Sciences, 2011
Bacteria form persisters, individual cells that are highly tolerant to different types of antibiotics. Persister cells are genetically identical to nontolerant kin but have entered a dormant state in which they are recalcitrant to the killing activity of the antibiotics. The molecular mechanisms underlying bacterial persistence are unknown.
Maisonneuve E   +3 more
openaire   +5 more sources

Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]

open access: yesPLoS ONE, 2017
Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse   +4 more
doaj   +1 more source

Rapid and Ultrasensitive Detection of Mutations and Genes Relevant to Antimicrobial Resistance in Bacteria

open access: yesGlobal Challenges, 2021
The worldwide emergence of multidrug‐resistant (MDR) bacteria is associated with significant morbidity, mortality, and healthcare costs. Rapid and accurate diagnostic methods to detect antibiotic resistance are critical for antibiotic stewardship and ...
François Huber   +7 more
doaj   +1 more source

Novel molecular markers for the detection of methanogens and phylogenetic analyses of methanogenic communities

open access: yesFrontiers in Microbiology, 2015
Methanogenic Archaea produce approximately one billion tons of methane annually, but their biology remains largely unknown. This is partially due to the large phylogenetic and phenotypic diversity of this group of organisms, which inhabit various anoxic ...
Lukasz eDziewit   +9 more
doaj   +1 more source

Structured RNA Contaminants in Bacterial Ribo-Seq

open access: yesmSphere, 2020
Ribosome profiling (Ribo-Seq) is a powerful method to study translation in bacteria. However, Ribo-Seq signal can be observed across RNAs that one would not expect to be bound by ribosomes.
Brayon J. Fremin, Ami S. Bhatt
doaj   +1 more source

Comparison of DNA and RNA sequencing of total nucleic acids from human cervix for metagenomics

open access: yesScientific Reports, 2021
Although metagenomics and metatranscriptomics are commonly used to identify bacteria and viruses in human samples, few studies directly compare these strategies.
Laila Sara Arroyo Mühr   +4 more
doaj   +1 more source

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