Structural signatures of thermal adaptation of bacterial ribosomal RNA, transfer RNA, and messenger RNA. [PDF]
PLoS ONE, 2017 Temperature adaptation of bacterial RNAs is a subject of both fundamental and practical interest because it will allow a better understanding of molecular mechanism of RNA folding with potential industrial application of functional thermophilic or ...
Clara Jegousse +4 more
doaj +1 more source
Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model
Heliyon, 2023 The SARS-CoV2 Omicron variants have acquired new Spike mutations leading to escape from the most of the currently available monoclonal antibody treatments reducing the options for patients suffering from severe Covid-19.
Cécile Hérate +13 more
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Dynamic insights on transcription initiation and RNA processing during bacterial adaptation [PDF]
, 2020 International audienceTranscription initiation and RNA processing govern gene expression and enable bacterial adaptation by reshaping the RNA landscape.
Serror, Pascale, +24 more
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RNA Viruses in Aquatic Unicellular Eukaryotes [PDF]
, 2021 Increasing sequence information indicates that RNA viruses constitute a major fraction of marine virus assemblages. However, only 12 RNA virus species have been described, infecting known host species of marine single-celled eukaryotes.
Ahola, Tero +5 more
core +1 more source
Global Challenges, 2021 The worldwide emergence of multidrug‐resistant (MDR) bacteria is associated with significant morbidity, mortality, and healthcare costs. Rapid and accurate diagnostic methods to detect antibiotic resistance are critical for antibiotic stewardship and ...
François Huber +7 more
doaj +1 more source
Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]
, 2010 The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core +1 more source
Structured RNA Contaminants in Bacterial Ribo-Seq
mSphere, 2020 Ribosome profiling (Ribo-Seq) is a powerful method to study translation in bacteria. However, Ribo-Seq signal can be observed across RNAs that one would not expect to be bound by ribosomes.
Brayon J. Fremin, Ami S. Bhatt
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Comparison of DNA and RNA sequencing of total nucleic acids from human cervix for metagenomics
Scientific Reports, 2021 Although metagenomics and metatranscriptomics are commonly used to identify bacteria and viruses in human samples, few studies directly compare these strategies.
Laila Sara Arroyo Mühr +4 more
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Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses:Implications for virus evolution and host persistence [PDF]
, 2004 Discrete RNA secondary and higher-order structures, typically local in extent, play a fundamental role in RNA virus replication. Using new bioinformatics analysis methods, we have identified genome-scale ordered RNA structure (GORS) in many genera and ...
Evans, David J +5 more
core +1 more source
Evaluation of rRNA depletion methods for capturing the RNA virome from environmental surfaces
BMC Research Notes, 2023 Objective Metatranscriptomic analysis of RNA viromes on built-environment surfaces is hampered by low RNA yields and high abundance of rRNA. Therefore, we evaluated the quality of libraries, efficiency of rRNA depletion, and viral detection sensitivity ...
Yuh Shiwa +5 more
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