Results 41 to 50 of about 2,082,862 (311)
Global discovery of bacterial RNA-binding proteins by RNase-sensitive gradient profiles reports a new FinO domain protein. [PDF]
, 2020 RNA-binding proteins (RBPs) play important roles in bacterial gene expression and physiology but their true number and functional scope remain little understood even in model microbes.
Vogel, Jörg +5 more
core +1 more source
mSystems, 2023 Both prokaryotic and eukaryotic RNAs can be 5′-capped by the metabolite nicotinamide adenine dinucleotide (NAD). Nudix hydrolases, such as bacterial NudC, specifically remove NAD-caps; however, the molecular and cellular functions of these ...
Milda Mickutė +10 more
doaj +1 more source
Study of E. coli Hfq's RNA annealing acceleration and duplex destabilization activities using substrates with different GC-contents [PDF]
, 2012 Folding of RNA molecules into their functional three-dimensional structures is often supported by RNA chaperones, some of which can catalyse the two elementary reactions helix disruption and helix formation.
Saxena, Krishna +6 more
core +1 more source
PLoS ONE, 2019 Sputum often contains large amounts of contaminating bacterial DNA that, if not eliminated during RNA isolation, may interfere with gene expression studies. During RNA isolation only repeated DNase treatment can effectively remove contaminating bacterial
Csilla Paska +3 more
doaj +1 more source
Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data
Frontiers in Microbiology, 2021 The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional ...
Amir Bar +3 more
doaj +1 more source
Mechanisms for activating bacterial RNA polymerase [PDF]
FEMS Microbiology Reviews, 2010 Gene transcription is a fundamental cellular process carried out by RNA polymerase (RNAP) enzymes and is highly regulated through the action of gene regulatory complexes. Important mechanistic insights have been gained from structural studies on multisubunit RNAP from bacteria, yeast and archaea, although the initiation process that involves the ...
Tamaswati, Ghosh +2 more
openaire +2 more sources
An RNA Surprise in Bacterial Effector Mechanisms [PDF]
, 2019 acterial pathogens secrete effector proteins to manipulate host signaling proteins and cellular structures. In this issue of Cell Host & Microbe, Pagliuso et al.
Vogel, Jörg, Gerovac, Milan
core +1 more source
Improved bacterial RNA-seq by Cas9-based depletion of ribosomal RNA reads. [PDF]
, 2020 A major challenge for RNA-seq analysis of gene expression is to achieve sufficient coverage of informative nonribosomal transcripts. In eukaryotic samples, this is typically achieved by selective oligo(dT)-priming of messenger RNAs to exclude ribosomal ...
Homberger, Christina +5 more
core +1 more source
Overlapping transcription and bacterial RNA removal [PDF]
Proceedings of the National Academy of Sciences, 2014 The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput strategies are available to identify the entire collection of RNA molecules produced by a cell population, which is currently known as ...
Lasa Uzcudun, Íñigo +1 more
openaire +5 more sources
The bacterial enhancer-dependent RNA polymerase [PDF]
Biochemical Journal, 2016 Transcription initiation is highly regulated in bacterial cells, allowing adaptive gene regulation in response to environment cues. One class of promoter specificity factor called sigma54 enables such adaptive gene expression through its ability to lock the RNA polymerase down into a state unable to melt out promoter DNA for transcription initiation ...
Zhang, N +4 more
openaire +3 more sources