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Regulating Bacterial Virulence with RNA [PDF]
Annual Review of Microbiology, 2017 International audienceNoncoding RNAs (ncRNAs) regulating virulence have been identified in most pathogens. This review discusses RNA-mediated mechanisms exploited by bacterial pathogens to successfully infect and colonize their hosts.
Juan J. Quereda +3 more
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Bacterial RNA Biology on a Genome Scale. [PDF]
Molecular Cell, 2018 Bacteria are an exceedingly diverse group of organisms whose molecular exploration is experiencing a renaissance. While the classical view of bacterial gene expression was relatively simple, the emerging view is more complex, encompassing extensive post ...
Jens Hör +8 more
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RNA Thermosensors in Bacterial Pathogens
, 2009 During the course of an infection, a pathogenic bacterium has to sense the environment and adjust its gene expression appropriately. One such environmental cue is the difference in temperature inside and outside the host. RNA thermosensors are structures
Johansson, Jörgen, +1 more
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An RNA Surprise in Bacterial Effector Mechanisms [PDF]
Cell Host & Microbe, 2019 acterial pathogens secrete effector proteins to manipulate host signaling proteins and cellular structures. In this issue of Cell Host & Microbe, Pagliuso et al.
Vogel, Jörg, Gerovac, Milan
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FEMS Microbiology Reviews, 2015 Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression.
Shepherd, Jennifer, Ibba, Michael
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Processing of bacterial RNA [PDF]
FEBS Letters, 1981 Processing of RNA is a feature of RNA metabolism which contributes to the determination of the fmal population of active RNA molecules in the cell. Pro- cessing is the sum of events which converts a primary RNA transcript into a functional molecule. RNA processing in bacteria consists mainly of two parts, modification of nucleotides and cutting and ...
Apirion, David, Gegenheimer, Peter
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Bacterial Small RNA Regulators [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2005 Small regulatory RNAs can modify the activity of proteins and the stability and translation of mRNAs. They have now been found in a wide range of organisms, and can play previously unsuspected critical regulatory roles. The bacterial small RNAs include two major classes.
Majdalani, Nadim +2 more
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RNA Thermometers in Bacterial Pathogens [PDF]
Microbiology Spectrum, 2018 ABSTRACT Temperature variation is one of the multiple parameters a microbial pathogen encounters when it invades a warm-blooded host. To survive and thrive at host body temperature, human pathogens have developed various strategies to sense and respond to their ambient temperature.
Loh, Edmund +4 more
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RNAs: regulators of bacterial virulence [PDF]
Nature Reviews Microbiology, 2010 RNA-based pathways that regulate protein expression are much more widespread than previously thought. Regulatory RNAs, including 5' and 3' untranslated regions next to the coding sequence, cis-acting antisense RNAs and trans-acting small non-coding RNAs, are effective regulatory molecules that can influence protein expression and function in response ...
Jonas Gripenland +5 more
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Regulatory RNA in Bacterial Pathogens [PDF]
Cell Host & Microbe, 2010 Bacteria constitute a large and diverse class of infectious agents, causing devastating diseases in humans, animals, and plants. Our understanding of gene expression control, which forms the basis for successful prevention and treatment strategies, has until recently neglected the many roles that regulatory RNAs might have in bacteria. In recent years,
Papenfort, K., Vogel, J.
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