Results 41 to 50 of about 2,524,971 (285)
PLoS ONE, 2019 Sputum often contains large amounts of contaminating bacterial DNA that, if not eliminated during RNA isolation, may interfere with gene expression studies. During RNA isolation only repeated DNase treatment can effectively remove contaminating bacterial
Csilla Paska +3 more
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Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data
Frontiers in Microbiology, 2021 The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional ...
Amir Bar +3 more
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The functional RNA cargo of bacterial membrane vesicles.
FEMS Microbiology Letters, 2018 Bacteria secrete RNAs, some of which have effects on other cells and on other species as signalling RNAs. Prokaryotic membrane vesicles (MVs) contain a range of RNA types.
Priscila Dauros-Singorenko +3 more
semanticscholar +1 more source
Viruses, 2020 In this study, we describe the biological function of the phage-encoded protein RNA polymerase alpha subunit cleavage protein (Rac), a predicted Gcn5-related acetyltransferase encoded by phiKMV-like viruses.
Pieter-Jan Ceyssens +13 more
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Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections
Frontiers in Immunology, 2023 BackgroundMicrobial infection is accompanied by remodeling of the host transcriptome. Involvement of A-to-I RNA editing has been reported during viral infection but remains to be elucidated during intracellular bacterial infections.ResultsHerein we ...
Zhi-Yuan Wei +30 more
doaj +1 more source
De novo assembly of bacterial transcriptomes from RNA-seq data
Genome Biology, 2015 Transcriptome assays are increasingly being performed by high-throughput RNA sequencing (RNA-seq). For organisms whose genomes have not been sequenced and annotated, transcriptomes must be assembled de novo from the RNA-seq data.
Brian Tjaden
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2016 IMPORTANCE Because clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others.
J. Herberg +22 more
semanticscholar +1 more source
An RNA Surprise in Bacterial Effector Mechanisms [PDF]
Cell Host & Microbe, 2019 Bacterial pathogens secrete effector proteins to manipulate host signaling proteins and cellular structures. In this issue of Cell Host & Microbe, Pagliuso et al. (2019) propose an effector mechanism in Listeria monocytogenes whereby an RNA-binding protein associates with bacterial RNA that stimulates RIG-I (retinoic acid inducible gene I)-based innate
Gerovac, Milan, Vogel, Jörg
openaire +3 more sources
Sotrovimab retains activity against SARS-CoV-2 omicron variant BQ.1.1 in a non-human primate model
Heliyon, 2023 The SARS-CoV2 Omicron variants have acquired new Spike mutations leading to escape from the most of the currently available monoclonal antibody treatments reducing the options for patients suffering from severe Covid-19.
Cécile Hérate +13 more
doaj
Novel Peptide Conjugates of Modified Oligonucleotides for Inhibition of Bacterial RNase P
Frontiers in Pharmacology, 2019 Novel alternatives to traditional antibiotics are now of great demand for the successful treatment of microbial infections. Here, we present the engineering and properties of new oligonucleotide inhibitors of RNase P, an essential bacterial enzyme.
Darya Novopashina +17 more
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