Results 41 to 50 of about 2,944,137 (233)
Bacterial ribonucleases and their roles in RNA metabolism
Critical reviews in biochemistry and molecular biology, 2019 Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent years, there has been a surge of new information about RNases and the roles they play in cell physiology.
D. Bechhofer, M. Deutscher
semanticscholar +1 more source
Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]
, 2011 Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit +6 more
core +2 more sources
Extracellular vesicles deliver Mycobacterium RNA to promote host immunity and bacterial killing
EMBO Reports, 2019 Extracellular vesicles (EVs) have been shown to carry microbial components and function in the host defense against infections. In this study, we demonstrate that Mycobacterium tuberculosis (M.tb) RNA is delivered into macrophage‐derived EVs through an M.
Yong Cheng, Jeff S. Schorey
semanticscholar +1 more source
Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host [PDF]
, 2019 A major gap in understanding infectious diseases is the lack of information about molecular interaction networks between pathogens and the human host.
Barnes, Stephen +9 more
core +1 more source
Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data
Frontiers in Microbiology, 2021 The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional ...
Amir Bar +3 more
doaj +1 more source
Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]
, 2017 Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K +11 more
core +3 more sources
RNA Dynamics in Aging Bacterial Spores [PDF]
Cell, 2012 Upon starvation, the bacterium Bacillus subtilis enters the process of sporulation, lasting several hours and culminating in formation of a spore, the most resilient cell type known. We show that a few days following sporulation, the RNA profile of spores is highly dynamic.
Segev, Einat +2 more
openaire +2 more sources
Quantitative bacterial transcriptomics with RNA-seq. [PDF]
Current Opinion in Microbiology, 2015 RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters, terminators, operons, among ...
J. Creecy, T. Conway
semanticscholar +3 more sources
PLoS ONE, 2019 Sputum often contains large amounts of contaminating bacterial DNA that, if not eliminated during RNA isolation, may interfere with gene expression studies. During RNA isolation only repeated DNase treatment can effectively remove contaminating bacterial
Csilla Paska +3 more
doaj +1 more source
De novo assembly of bacterial transcriptomes from RNA-seq data
Genome Biology, 2015 Transcriptome assays are increasingly being performed by high-throughput RNA sequencing (RNA-seq). For organisms whose genomes have not been sequenced and annotated, transcriptomes must be assembled de novo from the RNA-seq data.
Brian Tjaden
semanticscholar +1 more source