Results 41 to 50 of about 2,869,940 (329)

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

open access: yes, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

Bacterial ribonucleases and their roles in RNA metabolism

open access: yesCritical reviews in biochemistry and molecular biology, 2019
Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent years, there has been a surge of new information about RNases and the roles they play in cell physiology.
D. Bechhofer, M. Deutscher
semanticscholar   +1 more source

Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data

open access: yesFrontiers in Microbiology, 2021
The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional ...
Amir Bar   +3 more
doaj   +1 more source

Extracellular vesicles deliver Mycobacterium RNA to promote host immunity and bacterial killing

open access: yesEMBO Reports, 2019
Extracellular vesicles (EVs) have been shown to carry microbial components and function in the host defense against infections. In this study, we demonstrate that Mycobacterium tuberculosis (M.tb) RNA is delivered into macrophage‐derived EVs through an M.
Yong Cheng, Jeff S. Schorey
semanticscholar   +1 more source

Bacterial small RNAs in the Genus Rickettsia [PDF]

open access: yesBMC Genomics, 2015
Rickettsia species are obligate intracellular Gram-negative pathogenic bacteria and the etiologic agents of diseases such as Rocky Mountain spotted fever (RMSF), Mediterranean spotted fever, epidemic typhus, and murine typhus. Genome sequencing revealed that R. prowazekii has ~25 % non-coding DNA, the majority of which is thought to be either "junk DNA"
Casey L. C. Schroeder   +8 more
openaire   +3 more sources

Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies

open access: yesBMC Genomics, 2008
Background The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited.
Butcher Philip D   +3 more
doaj   +1 more source

Nasal Bacterial Microbiome: Probing a Healthy Porcine Family [PDF]

open access: yes, 2011
Upper respiratory tract (URT) infection caused the leading and devastating diseases in pigs. It was believed that the normal microbiome of URT plays a vital role in health and disease development.
Huanchun Chen, Min Yue, Weicheng Bei
core   +2 more sources

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]

open access: yes, 2008
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez   +77 more
core   +4 more sources

Comparison of five assays for DNA extraction from bacterial cells in human faecal samples [PDF]

open access: yes, 2020
Aim To determine the most effective DNA extraction method for bacteria in faecal samples. Materials and Results This study assessed five commercial methods, that is, NucliSens easyMag, QIAamp DNA Stool Mini kit, PureLink Microbiome DNA purification kit ...
Glorieux, Griet   +3 more
core   +1 more source

Elimination of bacterial DNA during RNA isolation from sputum: Bashing bead vortexing is preferable over prolonged DNase treatment.

open access: yesPLoS ONE, 2019
Sputum often contains large amounts of contaminating bacterial DNA that, if not eliminated during RNA isolation, may interfere with gene expression studies. During RNA isolation only repeated DNase treatment can effectively remove contaminating bacterial
Csilla Paska   +3 more
doaj   +1 more source

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