Alternative transcription cycle for bacterial RNA polymerase
Nature Communications, 2020 In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the ...
Timothy T. Harden +9 more
doaj +1 more source
Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system
Nucleic Acids Research, 2016 A central goal of synthetic biology is to implement diverse cellular functions by predictably controlling gene expression. Though research has focused more on protein regulators than RNA regulators, recent advances in our understanding of RNA folding and
Young Je Lee +3 more
semanticscholar +1 more source
Purification of Bacterial RNA from Infected Macrophages
Bio-Protocol, 2015 Studying the transcriptome of bacterial pathogens during infection is a very informative and effective tool for discovering genes that contribute to successful infection.
Lior Lobel +3 more
doaj +1 more source
Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community [PDF]
, 2018 Recent studies have conflicting data regarding the presence of intra-amniotic microbiota. Viral communities are increasingly recognized as important although overlooked components of the human microbiota.
Holtz, Lori R +2 more
core +2 more sources
Single-Cell RNA Sequencing of Plant-Associated Bacterial Communities
Frontiers in Microbiology, 2019 Plants in soil are not solitary, hence continually interact with and obtain benefits from a community of microbes (“microbiome”). The meta-functional output from the microbiome results from complex interactions among the different community members with ...
Qin Ma +5 more
doaj +1 more source
A Distinct Mechanism to Achieve Efficient Signal Recognition Particle (SRP)-SRP Receptor Interaction by the Chloroplast SRP Pathway [PDF]
, 2009 Cotranslational protein targeting by the signal recognition particle (SRP) requires the SRP RNA, which accelerates the interaction between the SRP and SRP receptor 200-fold.
Jaru-Ampornpan, Peera +2 more
core +2 more sources
The bacterial enhancer-dependent RNA polymerase
Biochemical Journal, 2016 Transcription initiation is highly regulated in bacterial cells, allowing adaptive gene regulation in response to environment cues. One class of promoter specificity factor called sigma54 enables such adaptive gene expression through its ability to lock ...
Nan Zhang +4 more
semanticscholar +1 more source
Cancer Medicine, 2023 Background Colorectal cancer (CRC) is known to present a distinct microbiome profile compared to healthy mucosa. Non‐targeted deep‐sequencing strategies enable nowadays full microbiome characterization up to species level.
Ainhoa Garcia‐Serrano +7 more
doaj +1 more source
Bio-Communication of Bacteria and its Evolutionary Interrelations to Natural Genome Editing Competences of Viruses [PDF]
, 2008 Communicative competences enable bacteria to develop, organise and coordinate rich social life with a great variety of behavioral patterns even in which they organise themselves like multicellular organisms.
Guenther Witzany
core +2 more sources
Toll-like receptor expression in C3H/HeN and C3H/HeJ mice during Salmonella enterica serovar Typhimurium infection [PDF]
, 2003 Here, we have investigated the mRNA expression of Toll-like receptor 2 (TLR-2), TLR-4, and MD-2 in spleens and livers of C3H/HeN mice (carrying wild-type TLR-4) and C3H/HeJ mice (carrying mutated TLR-4) in response to Salmonella infection.
Bryant, Clare E +4 more
core +2 more sources