Results 81 to 90 of about 2,524,971 (285)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

An improved bacterial mRNA enrichment strategy in dual RNA sequencing to unveil the dynamics of plant-bacterial interactions

Plant Methods
Background Dual RNA sequencing is a powerful tool that enables a comprehensive understanding of the molecular dynamics underlying plant-microbe interactions.
Jayabalan Shilpha, Junesung Lee, Ji-Su Kwon, Hyun-Ah Lee, Jae-Young Nam, Hakgi Jang, Won-Hee Kang   +6 more
doaj   +1 more source

Membrane vesicle-mediated release of bacterial RNA

Scientific Reports, 2015
Many Gram-negative bacterial species release outer membrane vesicles (OMVs) that interact with the host by delivering virulence factors. Here, we report for the first time that RNA is among the wide variety of bacterial components that are associated ...
Annika E. Sjöström, L. Sandblad, B. Uhlin, S. Wai   +3 more
semanticscholar   +1 more source

The amazing world of bacterial structured RNAs [PDF]

Genome Biology, 2010
The discovery of several new structured non-coding RNAs in bacterial and archaeal genomes and metagenomes raises burning questions about their biological and biochemical functions.
openaire   +3 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Agnodice: indexing experimentally supported bacterial sRNA-RNA interactions

mBio
In the last decade, the immense growth in the field of bacterial small RNAs (sRNAs), along with the biotechnological breakthroughs in Deep Sequencing permitted the deeper understanding of sRNA-RNA interactions.
Vasiliki Kotsira, Giorgos Skoufos, Athanasios Alexiou, Maria Zioga, Spyros Tastsoglou, Filippos S. Kardaras, Nikos Perdikopanis, Zacharopoulou Elissavet, Vasileios Gouzouasis, Theodosia Charitou, Artemis G. Hatzigeorgiou   +10 more
doaj   +1 more source

PCR-TTGE analysis of 16S rRNA from rainbow trout (Oncorhynchus mykiss) gut microbiota reveals host-specific communities of active bacteria. [PDF]

PLoS ONE, 2012
This study assessed the relative contributions of host genetics and diet in shaping the gut microbiota of rainbow trout. Full sibling fish from four unrelated families, each consisting of individuals derived from the mating of one male and one female ...
Paola Navarrete, Fabien Magne, Cristian Araneda, Pamela Fuentes, Luis Barros, Rafael Opazo, Romilio Espejo, Jaime Romero   +7 more
doaj   +1 more source

Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA

EMBO Reports, 2015
Toll‐like receptor (TLR) 13 and TLR2 are the major sensors of Gram‐positive bacteria in mice. TLR13 recognizes Sa19, a specific 23S ribosomal (r) RNA‐derived fragment and bacterial modification of Sa19 ablates binding to TLR13, and to antibiotics such as
A. Krüger, M. Oldenburg, C. Chebrolu, D. Beisser, J. Kolter, A. Sigmund, J. Steinmann, S. Schäfer, H. Hochrein, S. Rahmann, H. Wagner, P. Henneke, V. Hornung, J. Buer, C. Kirschning   +14 more
semanticscholar   +1 more source

Conformational flexibility of bacterial RNA polymerase [PDF]

Proceedings of the National Academy of Sciences, 2002
The structure of Escherichia coli core RNA polymerase (RNAP) was determined by cryo-electron microscopy and image processing of helical crystals to a nominal resolution of 15 Å. Because of the high sequence conservation between the core RNAP subunits, we were able to interpret the E.
Catherine A. Richter, Seth A. Darst, Gongyi Zhang, Natacha Opalka, Pablo Chacón, Willy Wriggers, Andrey Polyakov   +6 more
openaire   +3 more sources

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source