Results 201 to 210 of about 253,526 (264)

NAT10 as a central node in cancer biology: integrating epitranscriptomic regulation, metabolic reprogramming, and immune modulation. [PDF]

Front Immunol
Bo W, Yi Y, Zhao B, Dong H.
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Target DNA binding-induced dimerization is required for long-A prokaryotic Argonaute-mediated immunity

Swarts D, Barendse P, Drimmelen Mv, Pacesa M, Sivamaran A, Zhang D, Nickel L, Niault T, Lindhoud S, Roosjen M, Hegge J, Park K, Correia B, Oost Jvd, Joo C, Westphal A.   +15 more
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Structural insights into RNase H catalytic mechanism from room-temperature X-ray and neutron crystallography of apo- and RNA/DNA hybrid-bound enzyme. [PDF]

Curr Res Struct Biol
Gerlits O, Collins A, Kovalevsky A.
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Catalytic Properties of RNA

, 2015
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Mechanisms of catalytic RNA molecules

Biochemical Society Transactions, 2021
Ribozymes are folded catalytic RNA molecules that perform important biological functions. Since the discovery of the first RNA with catalytic activity in 1982, a large number of ribozymes have been reported. While most catalytic RNA molecules act alone, some RNA-based catalysts, such as RNase P, the ribosome, and the spliceosome, need protein ...
Dulce Alonso, Alfonso Mondragón
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The catalytic diversity of RNAs

Nature Reviews Molecular Cell Biology, 2005
The natural RNA enzymes catalyse phosphate-group transfer and peptide-bond formation. Initially, metal ions were proposed to supply the chemical versatility that nucleotides lack. In the ensuing decades, structural and mechanistic studies have substantially altered this initial viewpoint.
Martha J, Fedor, James R, Williamson
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RNA cleavage by small catalytic RNAs

Current Opinion in Structural Biology, 1995
Recent studies of the hammerhead ribozyme have provided an insight into its three-dimensional structure. In addition, studies using chemical probes, functional-group modification and mutational analysis, in combination with computer modelling, have led to proposals for the structure of both the hairpin and hepatitis delta virus ribozymes.
T, Tuschl, J B, Thomson, F, Eckstein
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SMALL CATALYTIC RNAs

Annual Review of Biochemistry, 1992
PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641 ROLLING CIRCLE REPLICATION REQUIRES SPECIFIC RNA CLEAVAGE . . . . . . . 643 SELF-CLEAVAGE OF RNA VIA THE HAMMERHEAD STRUCTURE.. . . . . . . . . . . . . . .
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In vitro selection of catalytic RNAs

Current Opinion in Structural Biology, 1994
In vitro selection techniques are poised to allow a rapid expansion of the study of catalysis by RNA enzymes (ribozymes). This truly molecular version of genetics has already been applied to the study of the structures of known ribozymes and to the tailoring of their catalytic activity to meet specific requirements of substrate specificity or reaction
K B, Chapman, J W, Szostak
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