Results 221 to 230 of about 253,526 (264)
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Structure‐Selective Catalytic Alkylation of DNA and RNA
Angewandte Chemie, 2012A variety of nucleic acids can be catalytically alkylated with rhodium-carbenoids generated from diazo compounds in aqueous buffer through an NH insertion process (see scheme; MES=2-(N-morpholino)ethanesulfonic acid). The method specifically targets unpaired bases such as those present in single strands, turn regions, and overhangs while leaving double-
Tishinov, Kiril +3 more
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The FASEB Journal, 1993
We describe the structures and catalytic properties of several naturally occurring self-cleaving RNA motifs that give 2', 3' cyclic phosphate products. The hammerhead and hairpin motifs are derived from plant pathogenic RNAs and the delta motif is part of the human hepatitis delta element. A fourth motif from Neurospora is less well characterized.
D M, Long, O C, Uhlenbeck
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We describe the structures and catalytic properties of several naturally occurring self-cleaving RNA motifs that give 2', 3' cyclic phosphate products. The hammerhead and hairpin motifs are derived from plant pathogenic RNAs and the delta motif is part of the human hepatitis delta element. A fourth motif from Neurospora is less well characterized.
D M, Long, O C, Uhlenbeck
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Antisense Catalytic RNAs as Therapeutic Agents
1994Publisher Summary This chapter presents an overview of well-characterized ribozymes with an emphasis on the problems that remain to be overcome before ribozyme therapy can be made a useful form of medical treatment. The chapter illustrates that many techniques are currently being used to enhance ribozyme activity.
D, Castanotto, J J, Rossi, N, Sarver
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Amplification, mutation and selection of catalytic RNA
Gene, 1989RNA, by virtue of its genotypic and phenotypic properties, is a suitable substrate for molecular evolution in the laboratory. We have developed techniques for the rapid amplification, mutation and selection of catalytic RNA. By combining these techniques in an iterative fashion, we are attempting to construct an RNA-based evolving system. Such a system
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Recent insights on RNA folding mechanisms from catalytic RNA
Cellular and Molecular Life Sciences (CMLS), 2000Methods for probing RNA structure in real time have revealed that initial folding steps are complete in less than a second. Refolding of large catalytic RNAs in vitro often results in long-lived intermediates that reach the native structure very slowly.
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A perspective on catalytic hydropyrolysis of biomass
Renewable and Sustainable Energy Reviews, 2021Magnus Zingler Stummann +2 more
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Biomedicine meets nanozyme catalytic chemistry
Coordination Chemistry Reviews, 2023Jinjun Shao, Changyu Cao
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