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Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source

Principles of <i>in vitro</i> selection of ribozymes from random sequence libraries. [PDF]

J R Soc Interface
Higgs PG, Muller UF.
europepmc   +1 more source

Epitranscriptomic Modulation of TET2 Inhibition Suppressed SARS-CoV-2 Infection and Blocked Viral Nucleocapsid Protein in Induced-Pluripotent-Stem-Cell-Derived Cardiomyocyte Screening Models. [PDF]

Biomater Res
Yang YP, Wang CH, Sun JR, Chien Y, Chien CS, Chiou GY, Cheng YH, Chen WT, Liu PC, Tsai SK, Chiang IH, Wang JC, Ou-Yang H, Ching LJ, Lo WL, Wang CY, Leu HB, Lee CY, Chiou SH.   +18 more
europepmc   +1 more source

Regulation of H3K4me3 breadth and MYC expression by the SETD1B catalytic domain in MLL-rearranged leukemia. [PDF]

Leukemia
Izumi S, Ohtani K, Matsumoto M, Shibata S, Rahmutulla B, Fukuyo M, Nishimoto M, Miyagawa H, Sakaida E, Yokote K, Kitabayashi I, Araki K, Kaneda A, Hoshii T.   +13 more
europepmc   +1 more source

Caspase Domain Duplication During the Evolution of Caspase-16. [PDF]

J Mol Evol
Eckhart L, Sachslehner AP, Steinbinder J, Fischer H.   +3 more
europepmc   +1 more source

Identification of potent multi-target antiviral natural compounds from the fungal metabolites against aspartyl viral polymerases. [PDF]

Sci Rep
Razavi ZS, Ramazani A, Zarei A.
europepmc   +1 more source

Biochemical analysis of human eIF4E-DCP2 interaction: Implications for the relationship between translation initiation and decapping. [PDF]

PLoS One
Mandell ZF, Coller J.
europepmc   +1 more source

Catalytic Properties of RNA

, 2015
openaire   +1 more source

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Mechanisms of catalytic RNA molecules

Biochemical Society Transactions, 2021
Ribozymes are folded catalytic RNA molecules that perform important biological functions. Since the discovery of the first RNA with catalytic activity in 1982, a large number of ribozymes have been reported. While most catalytic RNA molecules act alone, some RNA-based catalysts, such as RNase P, the ribosome, and the spliceosome, need protein ...
Dulce Alonso, Alfonso Mondragón
openaire   +2 more sources

The structure and function of catalytic RNAs [PDF]

Science in China Series C: Life Sciences, 2009
Before the discovery of ribozymes, RNA had been proposed to function as a catalyst, based on the discovery that RNA folded into high-ordered structures as protein did. This hypothesis was confirmed in the 1980s, after the discovery of Tetrahymena group I intron and RNase P ribozyme.
Lin Huang, Qi-Jia Wu, Yi Zhang
openaire   +2 more sources