Results 91 to 100 of about 502,163 (208)
PLoS ONE, 2012 RNA interference (RNAi) has previously been shown to be effective in western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) larvae via oral delivery of synthetic double-stranded RNA (dsRNA) in an artificial diet bioassay, as well as by ...
R. Bolognesi +15 more
semanticscholar +1 more source
Functional elucidation of lactate dehydrogenase in Toxoplasma gondii by double-stranded RNA gene suppression mediation. [PDF]
, 2005 Toxoplasma gondii is an intracellular parasite of humans and other mammals which can differentiate between an active and a dormant form. Our primary interest was to modulate gene expression in T.
Al-Anouti, Fatme
core +1 more source
Heliyon, 2021 Background: Emerging viruses could be detected before reaching pandemic level if universal viral detection screening was routinely used. Double-stranded RNA (dsRNA) is the only common antigen across most viral families.
Kornthara Kawang +5 more
doaj
3D RNA and functional interactions from evolutionary couplings [PDF]
arXiv, 2015 Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces research on their structure and functional interactions. We mine the evolutionary sequence record to derive precise information about function and structure of RNAs and RNA-protein complexes.
arxiv
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]
, 2013 Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Ingledew, W John +3 more
core +1 more source
Prediction of RNA pseudoknots by Monte Carlo simulations [PDF]
arXiv, 2004 In this paper we consider the problem of RNA folding with pseudoknots. We use a graphical representation in which the secondary structures are described by planar diagrams. Pseudoknots are identified as non-planar diagrams. We analyze the non-planar topologies of RNA structures and propose a classification of RNA pseudoknots according to the minimal ...
arxiv
Stability of a stochastically perturbed model of intracellular single-stranded RNA virus replication
, 2019 Replication of single-stranded RNA virus can be complicated, compared to that of double-stranded virus, as it require production of intermediate antigenomic strands that then serve as template for the genomic-sense strands.
Elena, Santiago F. +2 more
core +1 more source
Emerging role of endosomal toll-like receptors in rheumatoid arthritis [PDF]
, 2014 Toll-like receptors (TLRs) and their downstream signaling pathways have been comprehensively characterized in innate immunity. In addition to this function, these receptors have also been suggested to be involved in the pathogenesis of many autoimmune ...
Chamberlain, Giselle +2 more
core +2 more sources
RNA sampling and crystallographic refinement using Rappertk [PDF]
arXiv, 2007 Background. Dramatic increases in RNA structural data have made it possible to recognize its conformational preferences much better than a decade ago. This has created an opportunity to use discrete restraint-based conformational sampling for modelling RNA and automating its crystallographic refinement. Results.
arxiv
Genome Biology, 2017 Precise genome editing via homology-directed repair (HDR) after double-stranded DNA (dsDNA) cleavage facilitates functional genomic research and holds promise for gene therapy.
Jian-Ping Zhang +14 more
semanticscholar +1 more source