Results 201 to 210 of about 132,574 (309)

Longitudinal Repeatome Remodeling in Peripheral Blood Following Parkinson's Disease Diagnosis. [PDF]

Genes (Basel)
Kulski JK, Koks S.
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Spatial-quantitative profiling of intrahepatic HBsAg heterogeneity and clustered distribution in chronic HBV infection. [PDF]

JHEP Rep
Xu M, Zheng Y, Wu M, Qian Y, Lu W, Zhang P, Liu J, Li F, Song S, Zhang J, Zhang X, Zhang Z, Chen J, Yuan Z.   +13 more
europepmc   +1 more source

Transcription of Ribosomal, Heterogeneous Nuclear, and Messenger RNA in Eucaryotes

Cold Spring Harbor Symposia on Quantitative Biology, 1970
R. P. Perry, J. R. Greenberg, K. D. Tartof   +2 more
openaire   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Global transcriptional changes across multiple isogenic <i>C9orf72</i> patient iPSC-derived neurons. [PDF]

iScience
Sreeram A, Baron DM, Brusati A, Stallworth K, Humphrey J, Landers JE.   +5 more
europepmc   +1 more source

DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout

Advanced Science, EarlyView.
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li, Yesheng Wang, Chunmiao Yu, Siyu Hou, Elli Mylona, Plamena Naydenova, Jingyuan Zhao, Hong Yuan, Jingsong Duan, Hendrik F. P. Runge, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser   +12 more
wiley   +1 more source

Real-Time and Spatially Resolved Epigenetic Dynamics Tracking Beyond DNA Methylation via Live-Cell Epigenetic Sensors in 3D Systems. [PDF]

Biosensors (Basel)
Tariq A, Naz I, Arshad F, Chinnappan R, Mir TA, Khan MI, Yaqinuddin A.   +6 more
europepmc   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

The Heterogeneous Nuclear Ribonucleoprotein K (<i>hnrnpk</i>) Gene Targeted by miR-460a-5p Functions in the Gonadal Differentiation and Development in Chinese Tongue Sole (<i>Cynoglossus semilaevis</i>). [PDF]

Animals (Basel)
Li K, Yan H, Liu Q, Li W, Gao C, Chen S.
europepmc   +1 more source