Results 131 to 140 of about 8,401,372 (300)

Novel noncoding RNA candidates.

, 2012
Novel noncoding RNA candidates.
Rena Mizutani (169912), Hidenori Tani (169942), Keiko Tano (169945), Kenichi Ijiri (169951), Hiroshi Yoshida (169925), Naobumi Tochigi (169929), Takao Isogai (3113), Ai Wakamatsu (169916), Tadahiro Oonishi (169936), Yoshio Suzuki (169932), Nobuyoshi Akimitsu (169958), Noriyuki Tanaka (169920)   +11 more
core   +1 more source

Transcriptomic analysis reveals distinct expression patterns in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a common cause of drug‐resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response.
Shivani Sonawane, Michal Hendrych, Michaela Ručková, Robin Jugas, Jan Vrbský, Martin Pail, Barbora Straka, Martina Strnadová, Lenka Krsková, Adam Vácha, Miroslav Koblížek, Barbora Splítková, Kateřina Koželková, Eliška Hloušková, Tereza Vaňková, Josef Zámečník, Štefánia Aulická, Markéta Hermanová, Pavel Kršek, Ondřej Slabý, Milan Brázdil   +20 more
wiley   +1 more source

Long noncoding RNA expression profiling in cancer : challenges and opportunities

, 2019
In recent years, technological advances in transcriptome profiling revealed that the repertoire of human RNA molecules is more diverse and extended than originally thought.
Lorenzi, Lucia, Everaert, Celine, Speleman, Franki, Vandesompele, Jo, Decock, Anneleen, Avila Cobos, Francisco, Lefever, Steve, Verboom, Karen, Helsmoortel, Hetty, Volders, Pieter-Jan, Mestdagh, Pieter, Karen Verboom, Anneleen Decock, Lucía Lorenzi, Steve Lefever, Frank Speleman, Jo Vandesompele, Celine Everaert, Pieter Mestdagh, Hetty Helsmoortel, Francisco Avila Cobos, Pieter-Jan Volders   +21 more
core   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Data for: Divergent Expressed Gene Identified and Interaction Prediction of Long Noncoding RNA and mRNA Involved In Duck Reproduction

, 2017
Supplementary table data for “Divergent Expressed Gene Identified and Interaction Prediction of Long Noncoding RNA and mRNA Involved In Duck Reproduction”
Ren, J (via Mendeley Data), Ren, Jindong
core   +1 more source

A new cancer/testis long noncoding RNA, the OTP-AS1 RNA

Scientific Reports
The orthopedia homeobox (OTP) gene encodes a homeodomain-containing transcription factor involved in brain development. OTP is mapped to human chromosome 5q14.1.
Iuliia K. Karnaukhova, Dmitrii E. Polev, Larisa L. Krukovskaya, Andrei A. Makashov, Alexey E. Masharsky, Olga V. Nazarenko, Irina V. Poverennaya, Vsevolod J. Makeev, Ekaterina B. Akulova, Andrei P. Kozlov   +9 more
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Landscape of Noncoding RNA in the Hypoxic Tumor Microenvironment

Amidst the prevalent and notable characteristic of a hypoxic microenvironment present in the majority of solid tumors, a burgeoning number of studies have revealed the significance of noncoding RNAs (ncRNAs) in hypoxic tumor regions. The transcriptome of
Gui Qi, Haixia Zhang, Lianfeng Gong, Fei Yang, Zhaowu Ma, Chuanxin Zou   +5 more
core   +1 more source

Sorghum T2T pangenome highlights comprehensive genomic variation

iMetaOmics, EarlyView.
Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang, Chuanzheng Wei, Hope O. Okunbor, Xiaofei Deng, Die Hu, Yongfei Wang, Junli Du, Ephrem Habyarimana, Yongfu Tao, Yi‐Hong Wang, Jieqin Li   +10 more
wiley   +1 more source

Long noncoding RNA GAS5 acts as a competitive endogenous RNA to regulate GSK-3β and PTEN expression by sponging miR-23b-3p in Alzheimer’s disease

Neural Regeneration Research
Long noncoding RNA and microRNA are regulatory noncoding RNAs that are implicated in Alzheimer’s disease, but the role of long noncoding RNA-associated competitive endogenous RNA has not been fully elucidated.
Li Zeng, Kaiyue Zhao, Jianghong Liu, Mimin Liu, Zhongdi Cai, Ting Sun, Zhuorong Li, Rui Liu   +7 more
doaj   +1 more source