Results 161 to 170 of about 1,540,463 (333)
Interpretation of RNA Universe and Coding Potential Using IntRNA
Advanced Science, EarlyView.This study constructs a multi‐channel deep learning framework IntRNA to interpret RNA universe and coding potential. IntRNA consistently performed the best among existing methods in various benchmarks. Moreover, IntRNA’s interpretability is also validated by real‐world analysis, which found some features indicating long‐distance contact between ...
Yunxia Wang +8 more
wiley +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, EarlyView.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Mechanisms of alternative pre-messenger RNA splicing.
Annual Review of Biochemistry, 2003 D. Black
semanticscholar +1 more source
Advanced Science, EarlyView.A novel magneto‐active bone regeneration framework was engineered by integrating Fe3O4 nanoparticles with hydroxyapatite whiskers (HAw/Fe3O4). This composite acquired magnetic responsivity, enabling programmable microstructural alignment and amplified mechanobiological cues under magnetic fields, significantly enhancing osteogenesis and bone ...
Xue Zhang +8 more
wiley +1 more source
Analysis of trophic responses in lesioned brain: focus on basic fibroblast growth factor mechanisms
Brazilian Journal of Medical and Biological Research, 1998 The actions of fibroblast growth factors (FGFs), particularly the basic form (bFGF), have been described in a large number of cells and include mitogenicity, angiogenicity and wound repair.
Chadi G., Fuxe K.
doaj
Three decades of messenger RNA vaccine development
Nano Today, 2019 Rein Verbeke +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie +13 more
wiley +1 more source
Nanoscale platforms for messenger RNA delivery.
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2019 Bin Li, Xinfu Zhang, Yizhou Dong
semanticscholar +1 more source
Advanced Science, EarlyView.Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang +15 more
wiley +1 more source
Advanced Science, EarlyView.The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian +13 more
wiley +1 more source