Results 11 to 20 of about 325,444 (308)
, 2021 Messenger RNA medicines are basically sets of instructions and these instructions direct cells in the body to make proteins. mRNA plays a key role in human biology and it is a molecule that carries genetic code from DNA in a cell nucleus to ribosomes the protein making machinery of cells. Messenger RNA carries the genetic information copied from DNA in
Danny John
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Pseudo-messenger RNA: phantoms of the transcriptome. [PDF]
PLoS Genetics, 2006 The mammalian transcriptome harbours shadowy entities that resist classification and analysis. In analogy with pseudogenes, we define pseudo-messenger RNA to be RNA molecules that resemble protein-coding mRNA, but cannot encode full-length proteins owing
Martin C Frith +12 more
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From Viral Vaccines to Messenger RNA Vaccines
Pakistan Journal of Medicine and Dentistry, 2020 Today, the swiftness of epidemics of infectious disease is alarming. To date vaccines have been an enormous success for not only preventing but completely eradicating a number of malicious infectious disease like small pox, rubella, mumps, measles and ...
Saeeda Baig, Zoha Asghar
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Andrzej Dziembowski +3 more
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RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
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Technology in Cancer Research & Treatment, 2020 This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
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Vaccines against Coronavirus Type 19: An Overview [PDF]
Al-Anbar Medical Journal, 2023 Vaccines are biological agents that provide immunity against certain diseases [1]. Vaccination is an effective technique for prevention of infection and control outbreak of a wide range of infectious diseases (https://apps.who.int/iris/handle/10665 ...
Makwan Abdulkareem
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Cotranslational microRNA mediated messenger RNA destabilization
eLife, 2016 MicroRNAs are small (22 nucleotide) regulatory molecules that play important roles in a wide variety of biological processes. These RNAs, which bind to targeted mRNAs via limited base pairing interactions, act to reduce protein production from those ...
Trinh To Tat +4 more
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Lymph node CXCL17 messenger RNA: A new prognostic biomarker for colon cancer
Tumor Biology, 2018 Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as ...
Yomna Rashad +7 more
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Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]
, 2014 RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated
Nowak, Jakub S. +14 more
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