Results 111 to 120 of about 336,694 (310)

Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants

open access: yes, 2009
The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an ...
Kaaij, L.   +5 more
core   +1 more source

Low levels of ribosomal RNA partly account for the very high photosynthetic phosphorus-use efficiency of Proteaceae species [PDF]

open access: yes, 2013
Proteaceae species in south-western Australia occur on phosphorus- (P) impoverished soils. Their leaves contain very low P levels, but have relatively high rates of photosynthesis.
Ivakov, Alexander   +56 more
core   +1 more source

Annotation and functional prediction of RNA helicases in Ustilago maydis [PDF]

open access: yesIMA Fungus
RNA helicases are conserved enzymes found in both prokaryotes and eukaryotes. They function in all aspects of RNA metabolism and are known to influence various cellular and metabolic processes.
Amanda M. Seto, Barry J. Saville
doaj   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Base-specific spin-labeling of RNA for structure determination

open access: yes, 2007
To facilitate the measurement of intramolecular distances in solvated RNA systems, a combination of spin-labeling, electron paramagnetic resonance (EPR), and molecular dynamics (MD) simulation is presented. The fairly rigid spin label 2,2,5,5-tetramethyl-
Olav Schiemann   +16 more
core   +1 more source

Challenges of small RNA technology

open access: yes, 2020
Plant small RNAs are largely non-coding, regulatory RNAs that act with a sequence-specific binding capacity to regulate target gene expression, either before transcription, a process called transcriptional gene silencing (TGS), or after transcription, a ...
Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

Systemic movement of FT mRNA and a possible role in floral induction [PDF]

open access: yes, 2012
FLOWERING LOCUS T (FT) protein is known to be part of the mobile flowering inducing “florigen” signal in plants, but it may not be acting alone. This article reviews the data that FT mRNA can also move systemically throughout the plant and into the shoot
Hong, Yiguo   +5 more
core   +1 more source

RNA silencing response in chloroplast-replicating viroid siRNA biogenesis in plants

open access: yesPhytopathology Research
RNA silencing represents a cellular regulatory and defence mechanism in eukaryotes across kingdoms. In plants, a combined functionality of DCL2 and DCL3 is crucial for their synergistic defence against whilst DCL4 is required for nucleus-replicating ...
Pengcheng Zhang   +7 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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