Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo +6 more
wiley +1 more source
Circulation characteristics of bat coronaviruses linked to bat ecological factors in Korea, 2021-2022. [PDF]
VirulenceKim MC +13 more
europepmc +1 more source
Bacterial diversity in the honey sac during bee foraging on winter-flowering flora and dominant <i>Bacillus subtilis</i> inhibits <i>Hafnia alvei</i>. [PDF]
Front Insect SciWang M, Zhao W, Zhou D, Huang J.
europepmc +1 more source
Cancer Communications, EarlyView.Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao +11 more
wiley +1 more source
Case Report: A clinically relevant isolation of <i>Gardnerella leopoldii</i> guided by morphological and molecular evidence from a urinary tract infection case. [PDF]
Front Med (Lausanne)Chen L, Weng W, Li D, Xie W, Lu L, Li S.
europepmc +1 more source
Characteristics of Gut Microbiota in Patients with Erectile Dysfunction: A Chinese Pilot Study
The World Journal of Men's HealthPurpose: Little is known about the role of gut microbiota in the pathogenesis of erectile dysfunction (ED). We performed a study to compare taxonomic profiles of gut microbiota of ED and healthy males.
Jiaqi Kang +7 more
doaj +1 more source
Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases.
Infectious Disease Clinics of North America, 2016 Y. Doi, J. Wachino, Y. Arakawa
semanticscholar +1 more source
Cancer Communications, EarlyView.Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li +23 more
wiley +1 more source
In silico and structural analysis of Bacillus licheniformis FAO.CP7 pullulanase isolated from cocoa (Theobroma cacao L.) pod waste. [PDF]
BMC MicrobiolOgundolie FA +6 more
europepmc +1 more source
Chemistry &Biodiversity, EarlyView.Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández +3 more
wiley +1 more source